二氢吡唑邻甲酰氨基苯甲酰胺衍生物的合成及杀虫活性  

Synthesis and insecticidal activity of dihydro-pyrazole-carboxamides

作　　者：刘钢[1] 窦花妮[2] 孔小林[1,2] 谭成侠[1] 姚巍[2] 邢家华[2] 

机构地区：[1]浙江工业大学化学工程与材料学院,杭州310014 [2]浙江省化工研究院国家南方农药创制中心浙江基地,杭州310023

出　　处：《农药学学报》2011年第3期327-330,共4页Chinese Journal of Pesticide Science

基　　金：浙江省科技厅省属科研院所专项(2010F20009)

摘　　要：以邻氨基苯甲酸和4,5-二氢吡唑-5-甲酸为原料,制备得到苯并噁嗪酮,所得产物与取代胺作用制得8个结构新颖的二氢吡唑邻甲酰胺基苯甲酰胺类化合物,其结构用核磁共振氢谱和质谱进行了表征。生物活性试验结果表明,在500 mg/L质量浓度下,部分化合物对小菜蛾Plutella xylostella、苜蓿蚜Aphis medicaginis和稻飞虱Nilaparvata lugens的致死率达100%。Eight novel title compounds were synthesized from corresponding benzoxazinone with amines.The benzoxazinone was synthesized by corresponding 2-aminobenzoic acid and dihydro-1H-pyrazole-5-carboxylic acid.The structures of the compounds were confirmed by 1H NMR and MS.The results of biological tests indicated that the mortality of some of the title compounds was 100% against Plutella xylostella,Aphis medicaginis and Nilaparvata lugens at 500 mg/L.

关 键 词：邻氨基苯甲酸 二氢吡唑 合成 杀虫活性 

分 类 号：O626[理学—有机化学] O625.52[理学—化学]