抗平喘滴丸的制备工艺  

Study on the processing technology of antiasthmatic dropping pills

作　　者：周斌[1,2] 朱才庭 李雁霞[2] 朱才庆[2] 常军[1] 

机构地区：[1]江西科技师范学院药学院,江西南昌330013 [2]江西省药物研究所,江西南昌330029 [3]广东省罗浮山白鹤制药厂,广东惠州516133

出　　处：《中国生化药物杂志》2011年第3期206-208,共3页Chinese Journal of Biochemical Pharmaceutics

基　　金：江西省教育厅资助项目(GJJ08516)

摘　　要：目的研究抗平喘滴丸的制备工艺。方法在单因素考察基础上,以正交设计试验研究抗平喘滴丸的成型工艺。结果最佳成型工艺为药物组合物与基质比例为1∶2.5,药液温度为85℃,滴速为40滴/m in,冷却剂温度为(15±5)℃。结论由最佳工艺制备所得的滴丸硬度、圆整度和重量差异均符合要求。Purpose To optimize the preparation process of antiasthmatic dropping pills.Methods The processing technology was chosen by orthogonal decision based on the investigation of single affecting factor.Results The optimal processing technology was as follows：the ratio of drug mixtures to PEG was 1∶2.5,the temperature of drug liquid was 85,the dropping velocity was 40 drops per minute and the temperature of coolant liquid was（15±5）.Conclusion The dropping pills prepared through optimal technology had good hardness,roundness and weight difference.

关 键 词：抗平喘滴丸 麻杏石甘汤 工艺 

分 类 号：TQ460.6[化学工程—制药化工]