“神阙”穴隔药灸对荷瘤化疗大鼠胃粘膜保护作用的研究  

Experimental Study on Protective Action of Medicinal Moxibustion at Shenque(CV 8)Point on Gastric Mucosa in Rats Carring Tumor in Chemotherapy

作　　者：杨丹红[1] 江庆淇[1] 许文波[1] 

机构地区：[1]浙江中医学院针灸推拿系

出　　处：《中国针灸》1999年第8期484-485,共2页Chinese Acupuncture & Moxibustion

摘　　要：以荷Ｗ２５６大鼠为观察对象，观察“神阙”穴隔药灸抗肿瘤化疗药物氟尿嘧啶（５Ｆｕ）消化道毒性反应的疗效。结果显示：“神阙”穴隔药灸能促使胃粘膜ＰＧＥ２水平、胃粘膜血流量明显升高，使胃粘膜损伤指数降低，胃粘膜厚度较化疗组略有增厚。表明“神阙”穴隔药灸对化疗药物（５Ｆｕ）所致胃粘膜损伤有保护作用，此与其提高胃粘膜ＰＧＥ２水平、改善胃粘膜血流量有关。Therapeutic effect of medicinal moxibustion at“Shenque”(CV 8)point on toxic reaction of digestive tract induced by antineoplastic chemotherapeutic drug 5 flrorouracil(5 Fu)was observed in the rats carring tumor 256.Results indicated that medicinal moxibustion at “Shenque” (CV8)point could raise obviously PGE 2 level and volume of blood flow in gastric mucosa,decrease injury index of gastric mucosa,and slightly thicken gastric mucosa as compared with those of chemotherapy group.It is suggested that medicinal moxibustion at “Shenque”point has protective action on injury of gastric mucosa induced by 5 Fu, which is related to increase of PGE 2level and improvement of volume of bloof flow in gastric mucosa.

关 键 词：药灸 神阙穴 胃粘膜 药物作用 氟尿嘧啶 

分 类 号：R245.82[医药卫生—针灸推拿学]