小针电凝对SD大鼠真皮成纤维细胞活性影响的初步研究  

Initial research for the cytoactive of the fibroblast in the dermis of SD mice after treatment by fine-needle electrocoagulation

作　　者：于海生[1] 陈石海[1] 刘庆丰[1] 韦强[1] 廖明德[1] 蒙旭昌[1] 

机构地区：[1]广西医科大学第一附属医院整形美容外科,广西南宁530021

出　　处：《中国美容医学》2011年第5期759-760,共2页Chinese Journal of Aesthetic Medicine

基　　金：广西壮族自治区卫生厅自筹经费课题(编号:Z2008105)

摘　　要：目的:研究小针电凝对SD大鼠真皮成纤维细胞生长活性的影响,并探讨其可能的发生机制。方法:应用小针高频电凝分别在6J/H、8J/H、10J/H、12J/H功率下对SD大鼠真皮进行选择性电热解作用2s,然后分别在术后第14天、第35天取标本制成病理切片光镜下观察成纤维细胞和胶原纤维的数量变化。结果:经小针高频电凝作用后第35天的SD大鼠真皮中胶原纤维数量明显增加(P<0.05)。结论:小针高频电凝的适度选择性电热解作用可增加SD大鼠真皮中成纤维细胞的活性,增加其对胶原纤维的分泌,从而提示小针高频电凝对人体皮肤有非剥脱性除皱的作用。Objective To research the effects of the cytoactive of the Fibroblast in the dermis of SD Mice after selectional treatment by Fine-needle electrocoagulation,and infer the mechanism that results in the effects.Methods Using Fine-needle,the Dermis of SD Mice were electrolyzed selectionally at 6J/H、8J/H、10J/H、and 12J/H power.Then the specime,electrolyzed with Fine-needle,were made into the pathological sections on 14 and 35 days after electrocoagulation,the change of the fibroglia fibrils and the fibroblast would be observeed in photon microscope.Results The quantity of the fibroglia fibrils in the the dermis of SD mice were more incremental on 35 days after electrocoagulation than before that（P0.05）.Conclusions The quantity of the fibroglia fibrils that secreted by the Fibroblast,were increase in the dermis of the SD mice after moderately selectional electrocoagulation,and what manifest that the effects of nonablative skin rejuvenation can be obtained by electrocoagulation.

关 键 词：小针电凝 成纤维细胞 胶原纤维 非剥脱性除皱 

分 类 号：Q813.1[生物学—生物工程]