产碳青霉烯酶产气肠杆菌的ERIC-PCR图谱分析  

Map analysis of ERIC-PCR of carbapenemases-producing enterobacter aerogenes

作　　者：刘瑛[1] 费奇力[1] 陈峰[1] 陶晓勤[1] 刁文晶[1] 沈立松[1] 

机构地区：[1]上海交通大学医学院附属新华医院检验科,上海200092

出　　处：《中华医院感染学杂志》2011年第11期2176-2178,共3页Chinese Journal of Nosocomiology

摘　　要：目的了解医院临床产碳青霉烯酶产气肠杆菌感染流行情况,为医院感染控制提供帮助。方法对医院检验科微生物实验室在2009年6月-2010年3月临床分离出的16株产碳青霉烯酶产气肠杆菌及1株非产碳青霉烯酶产气肠杆菌,用肠杆菌基因间重复一致序列聚合酶链反应(ERIC-PCR)进行基因分型。结果 17株菌株分为两个克隆型,其中16株产碳青霉烯酶产气肠杆菌为同一型,而另1株非产酶菌株为另一型。结论医院存在产碳青霉烯酶产气肠杆菌克隆传播现象,医护人员应予以高度关注,并及时采取有效措施。OBJECTIVE To understand the infection prevalence of carbapenemases-producing Enterobacter aerogenes in hospital and provide supports for antibiotic policy and infection control.METHODS A total of 16 strains of carbapenems-producing E.aerogenes and 1 strain of E.aerogene were isolated from clinical laboratory of microbiology from Jun 2009 to Mar 2010.ERIC（Enterobacterial Repetitive Intergenic Consensus）-PCR was used to analyze the molecular epidemiology of the 17 isolates.RESULTS Totally 17 isolates were classified into two genotypes,in which 16 isolates were the same type,1 isolate was another type.CONCLUSION The results suggest that patients in ICU and the emergency ward exist the prevalence between carbapenemases-producing E.aerogenes.Health care workers should emphasis on this phenomenon and take effective measures.

关 键 词：碳青霉烯酶 产气肠杆菌 肠杆菌基因间重复一致序列聚合酶链反应 

分 类 号：R378[医药卫生—病原生物学]