洛伐他汀联合低分子肝素治疗颈动脉硬化症的疗效观察  

THERAPEUTIC EFFECTS OF LOVASTATIN COMBINED LOW MOLECULAR HEPARIN ON CAROTID ATHEROSCLEROSIS

作　　者：顾亚兰 

机构地区：[1]镇江市丹徒区人民医院内科,江苏镇江212000

出　　处：《承德医学院学报》2011年第2期139-141,共3页Journal of Chengde Medical University

摘　　要：目的:探讨洛伐他汀联合低分子肝素治疗颈动脉硬化症的临床疗效。方法:50例颈动脉硬化症患者随机分为两组,治疗组(25例)给予洛伐他汀联合低分子肝素治疗,对照组(25例)单纯应用洛伐他汀治疗,分别于治疗前和治疗后检测两组患者的粥样斑块面积及颈动脉内膜中层厚度(IMT)。结果:治疗组患者治疗后的颈动脉粥样斑块面积和IMT小于治疗组治疗前及对照组治疗后(P<0.01,P<0.05)。结论:洛伐他汀联合低分子肝素治疗颈动脉硬化症效果显著。Objective：To observe the effects of lovastatin combined low molecular heparin on carotid atherosclerosis.Methods：50 carotid atherosclerosis patients were randomly divided into treatment group and control group（n=25）：The patients in treatment group were administrated lovastatin and low molecular heparin while the patients in control group were administrated lovastatin only.The area of atheromatous plaque and IMT were respectively detected before and after treating.Results：The area of atheromatous plaque and IMT of patients in treatment group after treating were obviously smaller than that before treating and that of control group after treating（P0.01,P0.05）.Conclusions：Lovastatin combined low molecular heparin has significant effects on carotid atherosclerosis.

关 键 词：洛伐他汀 低分子肝素 颈动脉硬化症 

分 类 号：R543.4[医药卫生—心血管疾病]