Thirty Years of Multiple Sequence Codes  

作　　者：Edward N. Trifonov 

机构地区：[1]Genome Diversity Center, Institute of Evolution, University of Haifa, Haifa 31905, Israel [2]Division of Functional Genomics and Proteomics, Faculty of Science, Masaryk University, Brno 61137, Czech Republic

出　　处：《Genomics, Proteomics & Bioinformatics》2011年第1期1-6,共6页基因组蛋白质组与生物信息学报（英文版）

基　　金：supported by Grant 222/09 of Israel Science Foundation, and by Fellowship of SoMoPro (South Moravian Program, Czech Republic) with financial contribution of European Union within the seventh framework program (FP/2007-2013, Grant No. 229603)

摘　　要：An overview is presented on the status of studies on multiple codes in genetic sequences. Indirectly, the existence of multiple codes is recognized in the form of several rediscoveries of Second Genetic Code that is different each time. A due credit is given to earlier seminal work related to the codes often neglected in literature. The latest developments in the field of chromatin code are discussed, as well as perspectives of single-base resolution studies of nucleosome positioning, including rotational setting of DNA on the surface of the histone octamers.An overview is presented on the status of studies on multiple codes in genetic sequences. Indirectly, the existence of multiple codes is recognized in the form of several rediscoveries of Second Genetic Code that is different each time. A due credit is given to earlier seminal work related to the codes often neglected in literature. The latest developments in the field of chromatin code are discussed, as well as perspectives of single-base resolution studies of nucleosome positioning, including rotational setting of DNA on the surface of the histone octamers.

关 键 词：genomic code chromatin code second genetic code code interaction code degeneracy 

分 类 号：Q75[生物学—分子生物学]