硫氮卓酮治疗室上性心动过速疗效分析  

Analysis of the curative effects of diltiazem in treating supraventricular tachycardia

作　　者：史成军 赵化成 李青 秦莉 王子丽 邵忠 

机构地区：[1]山东省曹县人民医院,274400

出　　处：《中国现代医药杂志》2011年第6期76-78,共3页Modern Medicine Journal of China

摘　　要：目的观察硫氮卓酮与其他药物治疗室上性心动过速疗效并进行比较。方法 246例次经心电图证实的阵发性室上性心动过速(PSVT)发作,随机单盲分为硫氮卓酮、普罗帕酮、西地兰、维拉帕米、乙胺碘呋酮5个治疗组,观察各组疗效及不良反应,部分药物转复无效者采用同步直流电复律。结果转复成功率:硫氮卓酮组94.1%,普罗帕酮组75.0%,西地兰组64.1%,维拉帕米组89.3%,乙胺碘呋酮组72.7%。硫氮卓酮、维拉帕米组转复成功率较普罗帕酮、西地兰、乙胺碘呋酮组高,差异有显著性(P<0.01),硫氮卓酮组比维拉帕米组稍高,差异无显著性(P>0.05)。组间不良反应差异无显著性(P>0.05)。结论硫氮卓酮是治疗PSVT安全、有效的药物,病情合适者可作为首选药物之一。Objective To analysis the curative effects of diltiazem in treating supraventricular tachycardia and compare with other drugs.Methods 246 cases who were suffering paroxysmal supraventricular tachycardia（PSVT） were divided into five groups single-blindly,they were diltiazem group,propafenone group,cedilanid group,verapamil group and amiodarone group.The efficacys and side effects of each group were observed.Some noneffective cases were treated with synchronous direct current countershock.Results The cardoiversion success ratio were 94.1% for diltiazem group,75.0% for propafenone group,64.1% for cedilanid group,89.3% for verapamil group and 72.7%for amiodarone group.The cardoiversion success ratios of diltiazem group and verapamil group were higher than that of propafenone group,cedilanid group,and amiodarone group.The differences between them were significant（P0.01）.The cardoiversion success ratio of diltiazem group was a little higher than that of verapamil group,the difference between them was no significant（P0.05）.The side effects ratios between each groups were no significant（P0.05）.Conclusion Diltiazem is a secure,effetual medication for paroxysmal supraventricular tachycardia.For appropriate patient,diltiazem can be used as preference medicine.

关 键 词：硫氮卓酮 室上性心动过速 治疗 

分 类 号：R541.7[医药卫生—心血管疾病]