西藏那曲地区一起乡镇小学手足口病暴发疫情的调查  

Survey of a hand foot and mouth disease outbreak in primary school in Naqu,Tibet

作　　者：次仁顿珠[1] 欧珠[1] 罗桑平措[2] 

机构地区：[1]西藏自治区疾病预防控制中心,西藏拉萨850000 [2]西藏自治区第一人民医院

出　　处：《疾病监测》2011年第5期415-416,共2页Disease Surveillance

摘　　要：2009年9月13日开始西藏自治区那曲地区双湖特别行政区措折罗玛镇小学陆续出现以口腔和手掌疱疹为主要临床症状的病例,具体传染源不明,以直接接触传播为主,不能排除兼有呼吸道传播,病程6～12 d,疫情历时20 d,累积发病131例,年龄2～18岁,2～6岁病例11例,占发病总数的8.40%,7～18岁病例120例,占发病总数的91.60%,4例患者经咽拭子、粪便标本、疱疹液标本PCR核酸检测,肠道病毒71型(EV71)阳性,其余均为临床诊断,未出现重症和死亡病例,除10例患者在镇卫生院隔离输液治疗外,其他皆隔离后口服抗病毒药+维生素C治疗。通过综合防控措施,疫情得到了有效控制。Since 13 September 2009,the cases with the clinical symptoms of oral and hand herpes had been reported in a primary school in Shuanghu special administration area in Naqu prefecture in Tibet.The infection source was unknown.The major transmission route was person to person contact,but respiratory transmission could be excluded.The disease course was 12 days and the duration of the epidemic was 20 days.Totally 131 cases were reported.The age of the patients ranged from 2 to 18 years old.Eleven cases occurred in children aged 2-6 years（8.40%） and 120 cases in children/adolescents aged 7-18 years（91.60%）.PCR detection indicated that throat swabs,stool samples and herpes fluid samples collected from 4 cases were enterovirus 71 positive.The remaining cases were clinically diagnosed.No severe case and death occurred.Except 10 cases receiving intravenous transfusion treatment,the other cases were treated with oral antiviral drug plus vitamin C.By comprehensive prevention and control,the epidemic was effectively controlled.

关 键 词：手足口病 局部暴发 现场流行病学调查 综合性防控措施 

分 类 号：R181.3[医药卫生—流行病学]