抗生素在预防胸外科择期手术切口感染中的应用  

Preventive application of antibiotics to incised infection in opportunity selected thoracic surgery

作　　者：崔少罡[1] 陈维静[1] 常诚[1] 白玲[1] 谷晓军 李葳[1] 

机构地区：[1]解放军第264医院,太原030001

出　　处：《中华医院感染学杂志》1999年第4期208-210,共3页Chinese Journal of Nosocomiology

摘　　要：目的　探讨抗生素在预防胸外科择期手术切口感染中的合理应用。方法　按Ⅰ、Ⅱ、Ⅲ类切口对635 例胸外科择期手术分组进行抗生素的种类、应用时机、术后疗程等方面切口感染率的统计比较。结果　Ⅰ、Ⅱ、Ⅲ类切口感染率分别为2.56% 、4.39% 、7.54% ;青霉素类、喹诺酮类和头孢菌素类抗生素应用,切口感染率分别为10.05% 、3.23% 、2.83% 。术后抗生素应用疗程,Ⅰ、Ⅱ类切口感染率3 天以上无差异性,Ⅲ类切口感染率5 天以上无差异性。结论　预防性抗生素应用在胸外科择期手术中有确实的临床意义;Ⅱ、Ⅲ类切口的预防性抗生素以二、三代头孢菌素类或三代喹诺酮类为好。OBJECTIVE To explore the reasonable application of antibiotics to prevent incised infection in opportunity selected thoracic surgery were studied. METHODS According to incision types Ⅰ, Ⅱ and Ⅲ, 635 cases of opportunity selected thoracic surgery were divided into different groups and statistically compared about the incised infection rates of different antibiotics, applied opportunities, postoperative treatment courses and so on. RESULTS Infection rates of type Ⅰ, Ⅱ and Ⅲ incisions were 2.56%、4.39% and 7.54% respectively. With the application of penicillins, quinolones and cephalosporings, the incised infection rates were 10.05%、3.23% and 2.83% respectively. During postoperative antibiotic treatment courses, there were no difference in the infection rates of type Ⅰ and Ⅱ incision after 3 days or more and type Ⅲ incisions after 5 days or more. CONCLUSION Preventive antibiotic application has a clinical significance in opportunity selected thoracic surgery. For type Ⅱ and Ⅲ incisions, better preventive antibiotics are secondary and third generation of cephalosporins or third generation quinolonse. Penicillins are the best choice for type Ⅰ incision.

关 键 词：胸外科手术 切口感染 抗生素 预防 

分 类 号：R619.301[医药卫生—外科学] R655.05[医药卫生—临床医学]