高位硬膜外阻滞治疗冠心病临床观察  

Application of high epidural anesthesia in treatment of coronary heart disease

作　　者：刘锦[1] 刘晖[1] 屈军[1] 

机构地区：[1]广东医学院附属西乡人民医院麻醉科,广东深圳518000

出　　处：《海南医学院学报》2011年第6期735-737,共3页Journal of Hainan Medical University

基　　金：深圳市科技计划项目(200703116)~~

摘　　要：目的:探讨高位硬膜外阻滞治疗冠心病的临床疗效及对心率变异性的影响。方法:将60例冠心病患者,将期按治疗方法不同分为观察组和对照组,观察组30例患者在常规内科治疗的基础上采用高位硬膜外阻滞治疗,对照组30例患者采用常规内科治疗,对比分析两组疗效及心率变异性情况。结果:HRV治疗前后相比,观察组LF有显著性差异(P<0.05),对照组HF、LF/HF分别有显著性差异(P<0.05);观察组同对照组相比LF、HF、LF/HF均有显著性差异(P<0.05),心率变异性时域指标PNN50、RM SSD、SDNN、SDANN相比均有显著性差异(P<0.05),两组有效率相比有显著性差异(P<0.05),临床高位硬膜外阻滞并发症发生率低。结论:高位硬膜外阻滞治疗冠心病疗效肯定,与心率变异性相关,治疗安全可靠,临床值得推广。Objective： To discuss the effect of high epidural anesthesia（HEA） on coronary heart disease（CHD）.Methods： A total of 60 patients with CHD were divided into observation group and control group according to the different treatment methods by half.Patients in observation group were treated with HEA based on conventional internal medical treatment while patients in control group were treated with conventional treatment.Results： Compared with those before treatment,there was significant difference in LF of the observation group（P0.05）,and significant differences in HF and LF/HF of control group.There were significant differences in LF,HF,LF/HF,PNN50,RM SSD,SDNN,SDANN and efficacy between two groups（P0.05）.The incidence of complication due to high epidural anesthesia was lower in observation group.Conclusions： HEA is effective on CHD,and associated with heart rate variability.It is safe and worthy of clinical application.

关 键 词：高位硬膜外阻滞 冠心病 临床疗效 

分 类 号：R541.4[医药卫生—心血管疾病]