艾滋病患者眼科临床特点分析  

The clinical features of ocular manifestations in HIV/AIDS

作　　者：肖江[1] 何宏宇[2] 韩宁[1] 王凌航[1] 郜桂菊[1] 刘龙[1] 杨涤[1] 张黎颖[1] 赵红心[1] 毛羽[1] 

机构地区：[1]首都医科大学附属北京地坛医院感染一科,100085 [2]首都医科大学附属北京地坛医院眼科,100085

出　　处：《北京医学》2011年第6期470-473,共4页Beijing Medical Journal

基　　金：十一五重大专项"艾滋病机会性感染及减少HAART毒副反应的中医药治疗方案/方法的研究2008ZX10005-003;十一五重大专项"北京市朝阳区艾滋病和病毒性肝炎等重大传染病综合防治示范区建设研究2009ZX10004-903

摘　　要：目的阐明艾滋病患者HIV相关眼病的临床特征。方法回顾性研究了92例艾滋病患者的临床资料及眼科会诊记录。结果在HIV相关眼病患者中,HIV微血管病变者32例(34.8%),其次为视网膜炎25例(27.5%),免疫重建综合症后出现的全葡萄膜炎2例(2.2%)。在有或无HIV相关眼病患者中,伴有眼科症状的比例分别为28例(56.0%)和20例(47.6%);平均CD4水平分别为0.087×109/L和0.224×109/L(P<0.05)。结论 HIV微血管病变是主要的HIV相关眼病,其次为视网膜炎,且不同的眼科病变可以并存;CD4+T淋巴细胞低于0.05×109/L与HIV相关眼病的发生有关;必须对所有CD4+T淋巴细胞低于0.05×109/L的艾滋病患者完善常规眼科学筛查,以期早期发现HIV相关眼病。Objective To clarify clinical features of HIV-associated ocular diseases.Methods The clinical data and ophthalmic records in 92 cases of HIV/AIDS patients hospitalized from Oct.2008 to Feb.2010 have been collected and studied retrospectively.Results We found that,prevalence of retinopathy,was 34.8%;the second was retinitis（27.5%）;and the rate of uveitis in immune resonstitation syndrom patients was 2.2%.In HIV/AIDS patients with presence or absence of HIV-associated ocular diseases,prevalence of ocular manifestations were 56% and 47.6%（P 〉0.05）;mean CD4 counts were 0.087×109/L and 0.224×109/L cells/ul（P 〈0.05）,respectively.Conclusions Retinopathy was the most common HIV-associated ocular disease and the second was retinitis.CD4 count0.05×109/L was associated with HIV-associated ocular diseases,this highlighted routine ophthalmic screening in HIV/AIDS patients with CD4 count0.05×109/L.

关 键 词：艾滋病 HIV相关眼病 视网膜炎 微血管病变 

分 类 号：R512.91[医药卫生—内科学]