载香丹磷酸氢钙的研究  

Study on Dicalcium Phosphate Dihydrate Containing Xiangdan

作　　者：李茂红[1] 赵菊梅[1] 姚宁[2,3] 王玉锁[1] 李国庆[1] 屈树新[2] 

机构地区：[1]西南交通大学峨眉校区土木工程系,峨眉山614202 [2]西南交通大学材料科学与工程学院材料先进技术教育部重点实验室,成都610031 [3]西南交通大学生命科学与工程学院,成都610031

出　　处：《材料导报》2011年第12期16-18,共3页Materials Reports

基　　金：国家自然科学基金(50975239);中央高校基本科研业务费专项资金青年教师百人计划(SWJTU09BR271);西南交通大学峨眉校区科技团队项目(10801X10096001)

摘　　要：研究了湿法合成对香丹和磷酸氢钙的影响,以及温度和香丹添加量对磷酸氢钙载药量的影响。结果表明,湿法合成对香丹和磷酸钙氢钙均无明显影响,温度对香丹载入量影响较小,香丹载入量与合成体系中香丹添加量成正比。通过湿法合成制备载不同浓度香丹磷酸氢钙具有可行性。The effect of the wet synthesis methods on Xiangdan and dicalcium phosphate dihydrate was investigated. The effect of temperature and addition amount of Xiangdan on drug loading of dicalcium phosphate dihydrate was studied. The results show that the wet synthesis methods have no obvious effect on Xiangdan and dicalcium phos- phate dihydrate, the reaction temperature has a little effect on the drug loading of dicalcium phosphate dihydrate, and the drug loading of dicalcium phosphate dihydrate is ratio to the addition amount of Xiangdan. It is possible to prepare dicalcium phosphate dihydrate with various concentrations of Xiangdan.

关 键 词：磷酸氢钙 香丹 湿法合成 性质 载药量 

分 类 号：TB321[一般工业技术—材料科学与工程] R944.9[医药卫生—药剂学]