DL-2-萘普生热分解过程和非等温热分解动力学研究  

Thermal Decomposition and the Non-Isoththermal Decomposition Kinetics of DL-2-Naproxen

作　　者：周彩荣[1] 石晓华[1] 王海峰[1] 蒋登高[1] 

机构地区：[1]郑州大学化工与能源学院,河南郑州450001

出　　处：《高校化学工程学报》2011年第3期442-446,共5页Journal of Chemical Engineering of Chinese Universities

基　　金：河南省科技攻关资助项目(092102210177)

摘　　要：用热重-差热联用分析（DTA-TGA）技术和差动扫描（DSC）技术研究了DL-2-萘普生在空气中的热分解过程和非等温热分解机理及动力学。DTA-TGA分析表明DL-2-萘普生在（（250.72~296.87）±4.88）℃之间发生热分解反应,结合DSC分析表明DL-2-萘普生的熔点为（158.16±0.6）℃,熔融热为（140.57±2.10）J·g-1。运用Achar法和Coats-Redfern法对非等温动力学数据进行分析,得到热分解反应的机理函数和动力学参数,其热分解反应为二级反应机理,表观活化能为E=201.558 kJ·mol-1,指前因子A=7.52×1024 s-1。The thermal decomposition process and non-isothermal decomposition kinetic of DL-2-naproxen were studied by the Differential Thermal Analysis（DTA） and Thermogravimetric Analysis（TGA）.The results show that the thermal decomposition temperature of DL-2-naproxen is in the range of（（250.72~296.87）±4.88）℃.The melting point and the melting enthalpy of DL-2-naproxen were measured to be（158.16±0.6）℃ and（140.57±2.10） J·g-1,respectively,by Differential Scanning Calorimetry（DSC）.The mechanism function and kinetic parameters of non-isothermal decomposition of DL-2-naproxen were obtained from the analysis of DTA-TGA curves by both Achar and COATS-Redfern methods.The kinetic equation of DL-2-naproxen decomposition obtained shows that the decomposition reaction is a second order reaction,its activation energy and preexponential factor obtained are 201.558 kJ·mol-1 and 7.52×1024 s-1,respectively.The basic data obtained are available for the application,engineering design and industry production of DL-2-naproxen.

关 键 词：DL-2-萘普生 热分解 非等温热分解反应动力学 热失重分析 

分 类 号：TQ013.1[化学工程]