阿奇霉素不同联合用药方案在宫颈支原体感染的疗效对比  

Efficacy of azithromycin combining with different schemes in treatment of cervical mycoplasma infection:a comparative study

作　　者：华英英[1] 

机构地区：[1]杭州师范学院医学院附属余杭医院妇科,浙江杭州311100

出　　处：《中华医院感染学杂志》2011年第12期2600-2601,共2页Chinese Journal of Nosocomiology

摘　　要：目的比较阿奇霉素不同联合用药方案在宫颈支原体感染的疗效。方法选取2008年12月-2010年12月于本院进行治疗的90例宫颈支原体感染患者为研究对象,将其随机分为A组(阿奇霉素联合安尔碘组)45例和B组(阿奇霉素联合过氧化氢组)45例,后将两组患者的治疗总有效率、转阴率、不良反应发生率、复发率及患者满意率进行统计及比较。结果 A组的总有效率(97.78%)、转阴率(91.11%)及患者满意率(97.78%)高于B组的总有效率(86.67%)、转阴率(73.33%)及患者满意率(88.89%),复发率(4.44%)低于B组(20.00%),差异均有统计学意义(均P<0.05),而两组不良反应发生率均为11.11%,差异无统计学意义。结论阿奇霉素联合安尔碘的疗效优于阿奇霉素联合过氧化氢,在复发率方面也有优势,较受患者欢迎。OBJECTIVE To compare the efficacy of different combination schemes involving azithromycin in treatment of cervical mycoplasma infection.METHODS A total of 90 cases with cervical mycoplasma infections from Dec 2008 to Dec 2010 were selected as study object and randomly divided into group A（azithromycin joint AnEr iodine group） in 45 cases and group B（azithromycin joint hydrogen peroxide group） in 45 cases.After treatment,indicators such as total effective rate,adverse reactions,negativity incidence,recurrence rate between the two groups of patients were compared statistically.RESULTS The total effective rate of group A was 97.78%,which was lower than control group′s 86.67%,with shade rate 91.11% and patient satisfaction rate 97.78%,also lower than control′s 73.33%,88.89%,respectively.However,the recurrence rate was 4.44%,which was significantly lower than 20.00% in group B（P0.05）.Both groups had a adverse reaction rate of 11.11%.CONCLUSION The curative effect of azithromycin joint AnEr iodine is superior to hydrogen joint peroxide and is with the lower recurrence rate,which is welcome by the patients.

关 键 词：阿奇霉素 联合用药 宫颈支原体感染 疗效对比 

分 类 号：R978.1[医药卫生—药品]