老年人急性胆管炎CA19-9升高的临床意义  

CLINICAL SIGNIFICANCE OF ELEVATED CA19-9 LEVEL IN THE AGED PATIENTS IN ACUTE CHOLANGITIS

作　　者：张辉[1] 汪恭恕[1] 余昌俊[1] 

机构地区：[1]安徽医科大学第一附属医院普外科(十七病区),合肥230022

出　　处：《肝胆外科杂志》1999年第5期350-351,共2页Journal of Hepatobiliary Surgery

摘　　要：目的　探讨老年人急性胆管炎血清ＣＡ１９－ ９升高的临床意义。方法　放免法检测４５例老年人胆道良性疾病病人血清ＣＡ１９－ ９水平，将其分为三组：①慢性胆囊炎胆囊结石１８例；②急性胆囊炎１３例；③急性胆管炎１４例。结果　１２ 例急性胆管炎病人ＣＡ１９－ ９有不同程度升高（８５．７％ ），正常值为低于３０Ｋｕ／Ｌ，最高值达５００Ｋｕ／Ｌ；而急性胆囊炎病人中仅１例升高（７．７％ ），慢性胆囊炎胆囊结石病人中无１例升高。结论　ＣＡ１９－ ９本身并不完全是肿瘤标志物。老年人急性胆管炎也可致血清ＣＡ１９－ ９升高，随着病情的好转其值降为正常。临床上发现老年病人血清ＣＡ１９－ ９ 升高时，应先排除急性胆管炎所致。Objective To evaluate Clinical significance of elevated CA19-9 level in the aged patients with acute cholangitis .Metheds Serum CA19-9 was measured by RIA. 45 aged patients with benign biliary tract disease who were divided into three groups were studied:①calculous chronic cholecysttis(N=18);②acute cholecystitis(N=13);③acute cholangitis(N=14).Results 12 of fourteen patients with acute cholangitis had varied elevations of serum CA19-9(85.7%) ranging 30Ku/L～500Ku/L.Only 1 of thirteen patients with acute cholecystitis had elevation CA19-9(7.7%),none of patients with calculous chronic cholecystitis had CA19-9 elevation.Conclusion CA19-9 self is not an absolute tumor marker.A ged patients with cute cholangitis can show elevated CA19-9 level,which returns to normal after the disease is appropriately treated.Once serum CA19-9 is found to elevate in aged patients,acute cholangitis should be excluded firstly.

关 键 词：急性 胆管炎 CA19-9 肿瘤标志物 老年人 

分 类 号：R657.45[医药卫生—外科学]