老年缺血性脑血管病血瘀证患者的红细胞变形性及一氧化氮水平的检测及其意义  

Detection in erythrocyte deformabilities and levels of nitric oxide in senile patients with ischemic cerebrovascu-lar disease of blood stasis syndrome and its significance

作　　者：丁琪[1] 林美琴[1] 万勇[1] 朱静雯[1] 

机构地区：[1]安徽省立医院老年病科,安徽合肥230001

出　　处：《中国中西医结合急救杂志》1999年第10期460-461,共2页Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care

摘　　要：目的 :探讨老年缺血性脑血管病血瘀证患者的红细胞变形性及一氧化氮 ( NO)水平的变化。方法 :检测 5 5例老年缺血性脑血管病血瘀证患者的红细胞变形指数和 NO的水平。其中短暂性脑缺血发作 ( TIA) 2 5例 ,脑梗死 3 0例 ;另设 2 6例正常对照组作对比观察。结果 :血瘀证 TIA患者红细胞变形指数 ( 0 .4 67± 0 .14 5 )显著低于正常对照组 ( 0 .5 0 8± 0 .14 1) ,P<0 .0 5 ,脑梗死患者红细胞变形指数 ( 0 .4 43± 0 .15 6)降低更为明显( P<0 .0 1) ;NO水平 ,TIA患者与正常对照组比较无显著性差异 ( 79.10± 15 .3 7比 76.70± 17.10 ) ,而脑梗死患者 ( 88.5 0± 13 .68)显著升高。结论 :红细胞变形性改变及Objective:To investigate the variations in erythrocyte deformabilities( ED) and levels of nitric oxide( NO) in senile patients with ischemic cerebrovascular disease( ICVD) of blood stasis syndrome( BSS) . Methods:In 5 5 senile patients with ICVD of BSS the index of ED and levels of NO were detected.Among them 2 5 cases were transient ischemic attack( TIA) ,3 0 cases were cerebral infarction ( CI) .In addition 2 6normal subjects were established as a control group and the com parative observations were carried out.Results:In pa- tients with BSS the index of ED ( 0 .4 67± 0 .14 5 ) was significantly lower than that ( 0 .5 0 8± 0 .14 1) in control group ( P <0 .0 5 ) ,furthermore its decrease in patients with CI( 0 .4 43± 0 .15 6) was much m ore significant ( P<0 .0 1) .Regarding the variations in levels of NO in patients with TIA there were not significantdifferences ( 79.10± 15 .3 7vs.76.70± 17.10 ) compared with control group but in patients with CI they ( 88.5 0± 13 .68) were significant increased.Conclusions:Both the changes in ED and the increase in NO level in certain extent are related to the etiology and pathologic changes of senile ICVD of BSS.

关 键 词：血瘀 红细胞变形 一氧化氮 老年人 脑缺血 

分 类 号：R277.733.1[医药卫生—中医学]