深圳市宝安区美沙酮维持治疗者滥用甲基苯丙胺等非阿片类成瘾物质的情况调查  

INVESTIGATION ON NON-OPIOID ABUSE AMONG OUTPATIENTS RECEIVING METHADONE MAINTENANCE TREATMENT IN BAOAN DISTRICT OF SHENZHEN

作　　者：张泉水[1] 夏莉[2] 黎超雄[1] 蔡翠兰[1] 刘文红[1] 杨梅[1] 麦梅英[1] 

机构地区：[1]深圳市宝安区慢性病防治院,深圳518133 [2]深圳市宝安区西乡人民医院,深圳518102

出　　处：《中国药物依赖性杂志》2011年第3期232-234,共3页Chinese Journal of Drug Dependence

基　　金：深圳市宝安区科技计划项目(2009472)

摘　　要：目的:调查深圳市宝安区美沙酮维持治疗者使用非阿片类成瘾物质情况,为维持治疗策略提供科学依据。方法:对参加美沙酮维持治疗的符合条件的海洛因依赖者进行尿吗啡检测的同时,进行常见非阿片类成瘾物质尿检,包括甲基苯丙胺、亚甲基二氧基苯丙胺、氯胺酮、丁丙诺啡等,共完成160例。结果:美沙酮维持治疗者尿吗啡阳性率为36.2%。非阿片类成瘾物质甲基苯丙胺、亚甲基二氧基苯丙胺、氯胺酮、丁丙诺啡的阳性率分别为5.0%、1.2%、0.62%和0%。甲基苯丙胺阳性与吗啡阳性无相关性(2χ=1.458,P>0.05)。结论:美沙酮维持治疗者中存在多种成瘾物质滥用现象,非阿片类物质中最常用的是甲基苯丙胺,但与其是否仍在使用海洛因无相关性。Objective：To investigate non-opioid abuse among outpatients receiving methadone maintenance treatment（MMT） in Baoan District Shenzhen City and provide scientific basis for the management of MMT.Methods：Urine tests were conducted for morphine and non-opioid drugs such as methamphetamine,methylenedioxy amphetamine,ketamine,buprenorphine among 160 heroin addicts receiving MMT.Results：The positive rates of morphine,methamphetamine,methylenedioxy amphetamine,ketamine and buprenorphine were 36.2%,5.0%,1.2%,0.6% and 0%,respectively.There was no correlation between positive rates of methamphetamine and morphine.Conclusion：Polydrug abuse,especially,methamphetamine abuse commonly exists in MMT clinic,which needs public attention.

关 键 词：美沙酮维持治疗 药物滥用 非阿片类物质 

分 类 号：R512.91[医药卫生—内科学]