CpG序列的免疫激活机理及应用  

Mechanism and Applications of Immuno-stimulating CpG motifs

作　　者：陆军[1] 严维耀[1] 郑兆鑫[1] 

机构地区：[1]复旦大学遗传学研究所,上海200433

出　　处：《生物技术通报》1999年第5期30-33,共4页Biotechnology Bulletin

摘　　要：ＣｐＧ序列是一些在动物体内具有强烈的免疫激活功能的寡聚脱氧核苷酸。本文探讨了ＣｐＧ 序列在动物体内激活免疫反应的作用机理，概述了ＣｐＧ应用研究的进展，展望了ＣｐＧCpG motifs are oligodeoxynucleotides which have strong immuno-stimulating functions in animals. The mechanism of the immuno-stimulating effects caused by CpG motifs in animals is analysed and various applications of these effects are included. The future work on CpG motifs are also discussed.

关 键 词：CPG序列 作用机理 应激激酶 Thl类 免疫药剂 

分 类 号：R392.1[医药卫生—免疫学] R979.5[医药卫生—基础医学]