探讨药物的不同剂量配比对复方功效的影响  

Discussion on the Influence of Medicine Different Dosage Proportion to Compound Prescription Effect

作　　者：汤金波[1] 陈冠林[1] 许仕杰[1] 陈建南[1] 周福生[2] 赖小平[2] 

机构地区：[1]广州中医药大学,广东广州510405 [2]东莞广州中医药大学中医药数理工程院,广东东莞523808

出　　处：《辽宁中医杂志》2011年第6期1171-1172,共2页Liaoning Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金项目(30973945);广东省自然科学基金项目(200919802);广州中医药大学科研创新基金项目(10CX080);广州中医药大学(东莞)中医药数理工程研究院首期支撑项目(2007MECM001)

摘　　要：以黄连和吴茱萸以不同剂量配比组成的复方为讨论对象,首先分析了黄连和吴茱萸各自的药性,又对黄连和吴茱萸两味药以不同配比组成复方的药性配伍和功效表达进行了分析,结果发现其复方的药性配比几乎相同,而应用的范围却存在较大的差异,从而论证复方中剂量配比对药效的"制性存用"作用。Objective：In order to discuss the influence on the＂counteraction each other＇s nature without detracting from each other＇s effect＂to efficacy of compound prescription being due to different dosage proportion,this article selected the application of coptidis and evodia as the discussion object.Methods：First we analyzed the property of coptidis and evodia respectively.and then we analyzed the property compatability and efficacy expression of Chinese medical compounds being composed of huanglian and wuzhuyu with different proportion.Results：The results showed that those compounds＇ property compatibility was almost the same,but there exsited great difference in their application.which demonstrates the influence of medicine different dosage proportion to compound prescription effect.

关 键 词：黄连 吴茱萸 配伍剂量 药性配伍 制性存用 

分 类 号：R289[医药卫生—方剂学]