磁共振DWI值对病毒性脑炎和脑低级星形细胞瘤的鉴别诊断价值  

The Differential Value of DWI and ADC between Viral Encephalitis and Low Grade Astrocytomas

作　　者：李芳[1] 王振海[2] 陈兵[3] 王国玮[1] 

机构地区：[1]宁夏医科大学,银川750004 [2]宁夏医科大学总医院神经内科,银川750004 [3]宁夏医科大学总医院放射科,银川750004

出　　处：《宁夏医科大学学报》2011年第5期428-430,F0003,共4页Journal of Ningxia Medical University

基　　金：2007年国家自然科学基金面上项目(30760067);2007年宁夏自然科学基金项目(NZ09220)

摘　　要：目的探讨扩散加权成像(DW I)和表观扩散系数(ADC)值对病毒性脑炎和脑低级星形细胞瘤的鉴别诊断价值。方法 28例病毒性脑炎和27例脑低级星形细胞瘤在治疗前或手术前接受了常规MR I、DW I检查。病毒性脑炎经临床及治疗随访证实,脑低级星形细胞瘤病例经手术及病理证实。测量并计算两组病例DW I的表观扩散系数(ADC)值和相对表观扩散系数(rADC)值。结果病毒性脑炎平均ADC值和rADC值分别为(1.07±0.19)×10-3mm2/s和(1.26±0.21)×10-3mm2/s,脑低级星形细胞瘤平均ADC值和rADC值分别为(1.60±0.28)×10-3mm2/s和(2.04±0.41)×10-3mm2/s,差异均有统计学意义(P<0.01)。结论 DW I的ADC值和rADC值能较好地鉴别病毒性脑炎和脑低级星形细胞瘤。Objective To explore the differential value of diffusion weighted imaging （DWI） between viral encephalitis and low grade astrocytomas. Methods The conventional MR imaging and DWI were performed in 70 cases （28 cases with acute or subacute viral encephalitis and 19 cases with low grade astrocytomas） before treatments or operations. The diagnosis was made clinically in cases with viral encephalitis and were confirmed surgically and pathologically in cases with low grade astrocytomas. The apparent diffusion coefficient （ADC） values and relative apparent diffusion coefficient （rADC） values of the two group were calculated and analyzed. Re- sults The mean ADC values and rADC values were （ 1.07 ±0. 19） x 10^-3mm^2/s and （ 1.26±0.21 ） x 10^-3 mm^2/s respectively in the viral encephalitis; （ 1.60 ± 0.28） x 10 -3 mm^2/s and （2.04 ~ 0.41 ） x 10^-3 mm^2/s respectively in the low grade astrocytornas. There was significant ifferencein the mean ADC values （P 〈 0.05） and rADC values （P 〈 0.05） between the two groups. Conclusion The ADC value and rADC value of DWI play imoortant roles in the differential diagnosis between viral encephalitis and low grade astrocytomas.

关 键 词：病毒性脑炎 脑低级星型细胞瘤 DWI ADC值 

分 类 号：R445.2[医药卫生—影像医学与核医学]