2型糖尿病患者血清CA19-9水平分析及影响因素研究  

Study on serum CA19-9 levels and influencing factors in type 2 diabetic patients

作　　者：谢文秀[1] 杨璐[1] 曹悦鞍[1] 彭朝胜[1] 刘淑云[1] 

机构地区：[1]海军总医院特需医疗部,北京100048

出　　处：《现代医学》2011年第3期306-308,共3页Modern Medical Journal

摘　　要：目的:探讨2型糖尿病(T2DM)患者血清CA19-9水平的变化及相关影响因素。方法:选取T2DM患者100例,根据糖化血红蛋白(HbA1C)含量分为T2DM血糖控制不良组(HbA1C≥7%,49例)和T2DM血糖控制良好组(HbA1C<7%,51例),选取健康体检者50例为对照组。对比分析3组血清CA19-9水平的差异,并对血清CA19-9水平的影响因素进行相关分析。结果:T2DM血糖控制不良组血清CA19-9水平明显高于T2DM血糖控制良好组和对照组(P<0.05);T2DM血糖控制良好组血清CA19-9水平明显高于对照组(P<0.05)。CA19-9水平与HbA1C呈正相关(r=0.321 5,P<0.05)。结论:T2DM患者血清CA19-9水平高于正常人,且与血糖控制水平相关。Objective： To investigate the serum CA19-9 levels and influencing factors in diabetic patients.Methods： 150 subjects were divided into three groups,ie group of poorly controlled diabetics（HbA1C≥7%）（n=49）,group of moderately to well controlled diabetics（HbA1C〈7%）（n=51） and group of healthy control（n=50）.Serum CA19-9 level was comparatively analyzed.Pearson analysis was performed to value the relation between CA19-9 and influencing factors.Results： Serum CA19-9 level was significantly higher in the group of poorly controlled diabetics compared with moderately to well controlled diabetics and control group（P〈0.05）.It was also higher in the group of well controlled diabetics than control group（P〈0.05）.Pearson analysis showed a positive correlation between CA19-9 and HbA1C（r=0.321 5,P〈0.05）.Conclusion： Serum CA19-9 levels are increased in diabetic patients and correlate with the control of blood glucose.

关 键 词：2型糖尿病 血清CA19-9 糖化血红蛋白 

分 类 号：R587.1[医药卫生—内分泌]