蛋白质组学在妇科恶性肿瘤研究中的应用  

Application of Proteomics in the Research of Gynecological Malignant Tumors

作　　者：侯建章[1] 侯振江[2] 

机构地区：[1]沧州医学高等专科学校医学系外科教研室,河北沧州061001 [2]沧州医学高等专科学校医学技术系检验教研室,河北沧州061001

出　　处：《医学综述》2011年第11期1645-1647,共3页Medical Recapitulate

摘　　要：蛋白质组学技术能高通量对比健康和疾病状态时蛋白质表达谱的改变,有效地进行肿瘤标志物的筛选和鉴定,随着蛋白质组学研究方法的建立和发展,蛋白质组学技术在妇科肿瘤标志物的筛选、早期诊断和分类、病情监测、预后判断等方面有着重要意义。现在就蛋白质组学技术在乳腺癌、卵巢癌、宫颈癌等妇科恶性肿瘤研究中的应用进行综述。Proteomic techniques can realize high-throughput contrast of the protein expression spectrum between the healthy and disease state.It can screen and identify tumor markers efficiently.Along with the establishment and development of proteomics research methods,its significant role in the marker screening,early diagnosis and classification,condition monitoring,and prognosis etc.of gynecology tumor is coming into shape gradually.The application of proteomic techniques in the research of gynecological malignancy tumors such as breast cancer,ovarian cancer and cervical cancer is reviewed here.

关 键 词：蛋白质组学技术 乳腺癌 卵巢癌 宫颈癌 

分 类 号：R329.2[医药卫生—人体解剖和组织胚胎学] R373.3[医药卫生—基础医学]