252例药品不良反应报告回顾性分析  

A Retrospective Analysis of 252 Reports of Adverse Drug Reactions

作　　者：亓丰华[1] 梁凤[1] 赵珊[2] 

机构地区：[1]青岛大学医学院松山医院护理部,山东青岛266021 [2]青岛大学医学院松山医院药剂科,山东青岛266021

出　　处：《青岛医药卫生》2011年第3期181-183,共3页Qingdao Medical Journal

摘　　要：目的分析我院药品不良反应(ADR)的特点及引发ADR的相关因素。方法回顾性统计分析我院2005年7月至2009年12月收集的252例ADR报告。结果 252例ADR报告中,以静脉注射方式给药引发的ADR最多,占总例数的84.92%(214例);抗感染药物引起的ADR最多,占总例数的62.70%(158例);ADR表现以皮肤及附件损伤最为常见,占总例数的53.17%(134例)。结论上报的ADR例数与药品种类、给药途径等多种因素相关,应慎用注射剂,合理使用抗感染药物,以减少ADR的发生。Objective To study the characteristics and related factors of adverse drug reaction（ADR） in our hospital.Methods A total of 252 ADR cases collected from July 2005 to December 2009 in our hospital were retrospectively analyzed statistically.Results Of the total 252 ADR cases,most wereinduced by intravenous injection,which accounted for 84.92%（214 cases）;Most were induced by anti-infection drugs,which accounted for 62.70%（158 cases）;Most common clinical manifestations were the damage of skin and adnexa,which accounted for 53.17%（134 cases）.Conclusion The incidence of ADR is related to many factors,such as administration routes and category of drugs.Injections should be used rationally under careful observation.Rational use of anti-infection drugs should be emphasized to decrease the occurrence of ADR.

关 键 词：药物不良反应 合理用药 抗菌药物 

分 类 号：R969.3[医药卫生—药理学]