E—flow显像评价系统性硬化病患者指端微循环变化  

Assessment of fingertip ＇ s microcirculation changes in patients with systemic sclerosis by E-flow imaging

作　　者：张军辉[1] 李媛[1] 曹礼庭[1] 顾鹏[1] 张青[1] 张敏惠[1] 魏锦[2] 罗文峰[2] 

机构地区：[1]川北医学院附属医院超声科,四川省南充市637000 [2]川北医学院附属医院风湿血液科,四川省南充市637000

出　　处：《中华超声影像学杂志》2011年第5期413-416,共4页Chinese Journal of Ultrasonography

摘　　要：目的探讨高频超声结合Eflow显像评价系统性硬化病（systemic sclerosis，SSc）患者指端微循环病变的临床价值。方法SSc患者24例，正常对照组29例，均行高频超声检查并结合E—flow显像，观察各组受试者左右手中指末节指端血管分布特征、走行，测量指掌侧固有动脉、指腹动脉及甲床动脉收缩期峰值流速（PSV）、舒张末期流速（EDV）、平均血流速度（MV）、阻力指数（RI）及搏动指数（PI）。结果对照组末节指端血流信号丰富，可清晰显示指掌侧固有动脉、指腹动脉、甲床动脉及其细小分支；SSc末节指端血流显示欠清晰，连续性欠佳，血流分布明显减少。与对照组相比，SSc组中指末端指掌侧固有动脉、指腹动脉及甲床动脉PSV、EDV、MV均减低（P〈0．01），而RI及PI增高（P〈0．05）。对照组左右侧指端动脉血流参数无明显差异（P〉0．05），而SSc组左侧指掌侧固有动脉PSV、EDV及MV指标较右侧增高，差异均有统计学意义（P〈0．05）。结论高频超声结合E—flow显像可敏感、准确地反映SSc患者的指端微循环变化，为临床评价SSc患者微血管病变情况提供了新方法。Objective To investigate the clinical value of high frequency ultrasonography with E-flow imaging in the evaluation of fingertip＇s microcireulation changes in patients with systemic sclerosis（SSe）. Methods Twenty-four SSc patients and 29 healthy subjects were involved. High frequency ultrasonography with E-flow imaging was used to observe the configuration and distribution of digital arteries in the last segment of left and right middle finger. Peak systolic velocity （PSV）, end diastolic velocity （EDV）, mean velocity（MV）, vascular resistance index （RI） and pulsatility index（PI） of digital palmar propria arteries, nail bed arteries and finger ventral arteries were measured. Results In control group, rich blood supply was revealed within the fingertips. Digital palmar propria arteries,nail bed arteries and finger ventral arteries and their small branches were displayed clearly and continuously by E-flow imaging. While in SSc patients, the definition and continuity of fingertip＇s small vascular flow images were not as good as that in the control group,with the distribution of blood flow markedly reduced. Compared with the control group, PSV, EDV and MV of digital palmar propria arteries, nail bed arteries, finger ventral arteries were decreased in SSc group（ P 〈0.01）,but both RI and PI were increased（ P 〈0.05）. There were no statistically significant differences between left and right fingertip＇s arteries index in normal control group （ P 〉0.05）. But PSV, EDV and MV of left digital palmar propria arteries in SSc group were higher than that of the right（ P〈 0. 05） , whose differences bear statistic significance. Conclusions High frequency ultrasonography with Eflow imaging is sensitive and reliable to reflect fingertip＇s microcireulation changes and provide a new method to assess microvascular changes in SSc patients.

关 键 词：超声检查 硬化病 系统性 指 微循环 E—flow显像 

分 类 号：R593[医药卫生—内科学]