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作 者:王永森[1] 白锡波[1] 姬汉书[1] 张庆峰[1] 冀向宁[1] 郭艳汝[1]
机构地区:[1]河北省沧州市中心医院,河北省沧州市061001
出 处:《临床小儿外科杂志》2011年第3期204-206,共3页Journal of Clinical Pediatric Surgery
基 金:沧州市科学技术研究与发展指导计划(课题编号:09ZD34)
摘 要:目的探讨两种胃肠激素(神经降压素、胃动素)与婴幼儿原发性肠套叠的关系。方法采用放射免疫方法检测原发性肠套叠患儿24例(试验组)在发病当时(急性期)及空气灌肠复位后15d(恢复期)的空腹神经降压素、胃动素血浆水平,以及无肠道疾患的20例婴幼儿(对照组)两种激素的空腹血浆水平,并作比较。结果对试验组两种胃肠激素的检测值分别作急性期和恢复期的自身配对比较,差异均有显著统计学意义(P〈0.01)。试验组急性期两激素检测值与对照组分别作比较,差异均有显著统计学意义(P〈0.01),而恢复期试验组两激素检测值与对照组分别作比较,差异均无统计学意义(P〉0.05)。结论神经降压素和胃动素是参与婴幼儿原发性肠套叠发病机制的重要胃肠激素。Objective To detect the change of plasma levels of neurotensin and motilin in infant primary intussusceptions in both disease devolepement and after air enema reattachment, discuss about the relationship between the two gastrointestinal hormones and infant primary intussusception. Methods 24 samples of the testing group were collected from the infant primary intussusception patients in our hospital. 20 samples of control group were collected from the non-intestinal disorders cases of infants, samples of blood were taken from the infants who are the in the testing group in both disease devolepement and after air enema reattachment 15 days ; and the infants who are in the control group. Both motilion and neurotensin were detected by radioimmunoassay. The test data were analyzed with SPSS 13.0 software. Results In the testing group, the plasma levels of neurotensin and motilin on the onset are higher than that of 15 days after air enema reattaehment. The difference between the plasma levels of neurotensin and motilin on the onset in the test group with that of the control group are statistically significant. The difference between plasma levels of neurotensin and motilin 15 days after air enema reattachment in the test group with that of the control group is no statistically significant. Conclusion Neurotensin and motilin are all important gastrointestinal hormones what have relationship of the nosogenesis in infant primary intussusceptions.
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