ANCA相关性小血管炎误诊为肺结核3例并文献复习  

ANCA Associated Systemic Vasculitis:Report of 3 Cases Misdiagnosed as Pulmonary Tuberculosis and Review of the Literature

作　　者：陈乐蓉[1] 邹禄如[1] 

机构地区：[1]江西省胸科医院内1科,江西南昌330006

出　　处：《中国现代医生》2011年第18期170-172,共3页China Modern Doctor

摘　　要：目的探讨抗中性粒细胞胞浆抗体(antineutrophil cytoplasmic antibodies,ANCA)相关性小血管炎的临床表现及早期诊断要点。方法分析2006～2010年间我院收治的3例ANCA相关性小血管炎患者的临床资料,并复习国内外文献。结果 3例患者均为男性,年龄43～71岁,C-ANCA阳性1例,P-ANCA阳性2例,其中1例曾患甲亢,曾服用丙基硫氧嘧啶。3例患者诊断明确前均误诊为肺结核,ANCA对其确诊有重要意义。结论 ANCA相关性小血管炎临床表现不典型,除肺部症状外,常累及多器官、多系统,误诊率高,ANCA检测有助于AASV早期诊断和治疗。Objective To investigate the clinical manifestations and the early diagnosis of ANCA associated systemic vasculitis. Methods 3 cases ANCA associated systemic vaseulitis were reported and the literatures were reviewed. Results All 3 cases were men. c-ANCA were positive in 1 case and p-ANCA were positive in another 2 eases. 1 case had been diagnosed hyperthyroidism and had taken propyhhiouracil. 3 cases were all misdiagnosed as pulmonary tuberculosis before they were diagnosed correctly. ANCA was very important to make a definite diagnosis. Conclusion The clinical manifestation of ANCA associated systemic vasculitis are not typical,multiple organs and systems damaging are often occurred besides the lung. ANCA and specific antigens tests may help the early diagnosis and treatment.

关 键 词：抗中性粒细胞胞浆抗体 血管炎 

分 类 号：R543[医药卫生—心血管疾病]