设计合成亚胺类化合物用于金属阳离子逻辑门识别及双控荧光分子开关构建  

Design and Synthesis of Imine Compound for Metal Cation Logical Gates Recognition and Setup of Double-Control Fluorescent Molecule Switch

作　　者：黄韬[1] 朱玉莲[2] 戴雪芹[1] 张岐[1,2] 黄燕[2] 

机构地区：[1]海南大学海南精细化工重点实验室,海南海口570228 [2]江苏大学化学化工学院,江苏镇江212013

出　　处：《光谱学与光谱分析》2011年第7期1834-1837,共4页Spectroscopy and Spectral Analysis

基　　金：国家自然科学基金项目(20871061);海南大学奖励基金项目(hd09xm07/24);江苏省科技支撑计划(SBE201077304);海南自然科学基金项目(209001)资助

摘　　要：报道了首次设计合成希夫碱还原产物N,N-双(4-甲氧基苯)乙基-1,2-二胺受体分子L。通过考察L与12种金属阳离子作用时的荧光性质变化,发现Cu2+和Fe3+对L有显著的荧光猝灭作用,Zn2+和Cd2+对L有明显的荧光增强作用;因此可构建受体分子L对两对金属阳离子的"OR"逻辑门作用关系,形成逻辑识别体系。测定了ZnL的单晶结构(单斜晶系,CCDC No.747994),结合波谱表征手段推测了其他同系列金属配合物的分子结构。依据ZnL良好的荧光特性及与邻近金属元素离子的可逆交换作用,设计了Zn2+/ZnL/Co2+,Zn2+/ZnL/Ni2+双控荧光分子开关。作者希望该工作能对促进分子计算机和生物智能化医疗检测理论与配套设备研制的发展起到积极作用。The Schiff base＇s reduced product N,N-bis（4-methoxybenzyl） ethane-1,2-diamine,which was used as a receptor L,was designed and synthesized for the first time in the present article.It was found that Cu2＋ and Fe3＋ could quench L in fluorescence observably and Zn2＋ and Cd2＋ could enhance L remarkably.So the two pair metal cation could set up ＂OR＂ logical gate relation with the receptor molecule L,then a logical recognition system be formed.The data of resolved ZnL＇s single crystal indicated that ZnL belonged to monoclinic（CCDC No.747994）.Integrated spectrum instrument was used to characterize the structure of its alike series of complex compound.According to ZnL＇s excellent fluorescence character and the ability to exchange with contiguous metal cation,Zn2＋/ZnL/Co2＋,Zn2＋/ZnL/Ni2＋ fluorescent molecule switch was designed.It is hoped that the work above could be positive for the development of molecule computer,bio-intellectualized inspection technology（therapy） and instrument.

关 键 词：亚胺 逻辑门 荧光开关 阳离子识别 等温滴定微量热仪 

分 类 号：O657.3[理学—分析化学]