清开灵颗粒体外抑菌作用研究  

Study on the antibacterial effect of Qingkailing particles

作　　者：何军[1] 黄清松[2] 

机构地区：[1]广州白云山明兴制药有限公司医学部,广东广州510250 [2]广东药学院基础学院,广东广州510006

出　　处：《赣南医学院学报》2011年第2期192-193,共2页JOURNAL OF GANNAN MEDICAL UNIVERSITY

摘　　要：目的:观察清开灵颗粒的体外抑菌作用。方法:采用纸片药敏试验法和二倍稀释法,测定清开灵颗粒对乙型溶血性链球菌、甲型溶血性链球菌、肺炎双球菌、金黄色葡萄球菌、流感杆菌的敏感程度和最低抑菌浓度。结果:清开灵颗粒对乙型溶血性链球菌、甲型溶血性链球菌、肺炎双球菌、金黄色葡萄球菌、流感杆菌的最低抑菌浓度(M IC)分别为:0.031 3 g/mL、0.031 3 g/mL、0.062 5 g/mL、0.031 3 g/mL、0.062 5 g/mL。结论:清开灵颗粒对乙型溶血性链球菌、甲型溶血性链球菌、肺炎双球菌、金黄色葡萄球菌、流感杆菌均有较好的抑菌作用。Objective：To observed the antibacterial of Qingkailing particles in vitro.Methods：To determinate inhibition of Qingkailing particles for hemolytic streptococcus,alpha hemolytic streptococcus,Streptococcus pneumoniae,Staphylococcus aureus and Minimum inhibitory concentration.Results：MIC of the Qingkailing particles on beta hemolytic streptococcus,alpha hemolytic streptococcus,Streptococcus pneumoniae and Staphylococcus aureus were：0.031 3 g/mL;0.031 3 g/mL;0.062 5 g/mL;0.031 3 g/mL and 0.062 5 g/mL.Conclusion：Qingkailing particles have good antimicrobial effect on beta hemolytic streptococcus,alpha hemolytic streptococcus,Streptococcus pneumoniae and Staphylococcus aureus.

关 键 词：清开灵颗粒 最低抑菌浓度(MIC) 乙型溶血性链球菌 甲型溶血性链球菌 肺炎双球菌 金黄色葡萄球菌 流感杆菌 

分 类 号：R965[医药卫生—药理学]