柔嫩艾美耳球虫早熟株的内生发育及其致病性  

Endogenous Developmental Stages and Pathogenicity of Precocious Strain of Eimeria tenella

作　　者：刘群[1] 蒋金书[1] 

机构地区：[1]中国农业大学动物医学院,北京100094

出　　处：《中国兽医学报》1999年第6期569-571,共3页Chinese Journal of Veterinary Science

基　　金：国家攀登计划畜禽重大疫病防治项目

摘　　要：为了给鸡球虫早熟弱毒疫苗的开发提供依据,对柔嫩艾美耳球虫(Eim eria tenella) 北京株经10 代早熟选育获得的早熟株的内生发育研究发现,其第2 代裂殖生殖发育较快,第2 代裂殖体含裂殖子较少,提前进入配子生殖,从而造成卵囊“早熟”。该早熟株致病性大大下降,经口感染10×104 个/只的致病性仅相当于剂量0.1×104 个/只亲本毒株的致病性。该虫株可作为研制早熟弱毒苗用虫株。One precocious strain was derived from the Beijing strain of E.tenella. Examination of endogenous developmental stages suggested that the development of second generation schizogony of the precocious strain was earlier and the schizozoites fewer than that of the parental strain. In addition, the pathogenicity of precocious strain was found to be attenuated markedly. The inoculation effect of 10×10 4 oocysts of the precocious strain appears similar to that of 0.1×10 4 oocysts of the parental strain.

关 键 词：柔嫩艾美耳球虫 早熟株 致病性 内生发育 

分 类 号：S852.723[农业科学—基础兽医学]