105例丹参注射液不良反应的回顾性研究  

Retrospective analysis of 105 cases of adverse reaction of salvia miltiorrhiza injection

作　　者：柯昌毅[1] 陈伟峰[1] 

机构地区：[1]重庆市第三人民医院药剂科,400014

出　　处：《重庆医学》2011年第18期1795-1796,共2页Chongqing medicine

摘　　要：目的分析丹参注射液不良反应的特点,以规范使用丹参注射液。方法回顾性分析本院应用丹参注射液出现不良反应的105份临床病历,分析患者性别、年龄、过敏史、原发疾病、不良反应出现时间、程度及其临床表现类型与发生不良反应的关系。结果男性、超过60岁、静脉滴注开始30 min、滴注后及有过敏史的患者不良反应发生率较高,主要为中度不良反应,其临床表现主要为过敏反应、皮肤及消化系统反应。结论丹参注射液在临床上广泛应用,其出现的不良反应应该引起人们的高度重视。Objective To analyze the characteristics of adverse reactions of salvia miltiorrhiza injection and standardize its administration.Methods 105 cases of adverse reactions of salvia miltiorrhiza injection documented in medical records in our hospital were analyzed retrospectively,and patients＇ gender,age,history of allergies,primary diseases,time and extent of adverse reaction occured and its clinical manifestations were investigated and their relations with adverse reactions were studied.Results Incidence rates of adverse reaction were higher for patients who were male,over 60-year old,occurred adverse reactions in the first 30 min of or after intravenous infusion,and with history of allergies.The major clinical manifestations were allergic reaction,dermoreaction and digestive system responses which mainly were moderate.Conclusion Salvia miltiorrhiza injection is widely used in clinic,and its adverse reactions should be aroused great attention.

关 键 词：丹参 药物不良反应 回顾性研究 

分 类 号：R286[医药卫生—中药学]