慢性肾脏疾病心血管事件临床分析及危险因素研究  

The Study for cardiovascular events in chronic kidney disease and risk factors

作　　者：安宏元[1] 陈杰翔[2] 

机构地区：[1]泸州医学院临床医学系,四川泸州646000 [2]泸州医学院附属医院泌尿外科,四川泸州646000

出　　处：《四川医学》2011年第5期663-664,共2页Sichuan Medical Journal

摘　　要：目的研究慢性肾脏疾病合并心血管事件的危险因素。方法本研究纳入2009年3月~2010年4月我院心内科、肾脏内科住院患者33例。按1：2配对原则选择同期住院的未合并心血管事件慢性肾脏疾病患者66例。以单因素分析及Logistic多因素分析法分析患者合并心血管事件危险因素。结果①纳入肾脏病合并心血管事件33例,平均（49.86±10.21）岁;②单因素分析显示左室肥厚、血压、左室射血分数及估算肾小球滤过率两组之间差异有统计学意义（P〈0.05）;③多因素分析结果显示,肾小球滤过率,左室肥厚和糖尿病肾病有统计学意义。结论心血管事件是慢性肾脏疾病常见合并症,危险因素多,须引起高度重视。Objective To study the risk factors of chronic kidney disease with cardiovascular events.Methods 33 chronic kidney disease cases hospitalized at nephrology or cardiology department from March 2009 to April 2010 complicated with cardiovascular events were enrolled in this study.With 1∶2 match-selection,66 patients with chronic kidney disease no suffering from cardiovascular events were enrolled as control group.To observes their risk factors for cardiovascular events,we analyzed their clinical data,then taken single factor analysis and Logistic multivariate analysis method.Results ①The kidney disease with cardiovascular events in 33 patients with mean age（49.86±10.21） years were enrolled;② Univariate analysis showed that left ventricular hypertrophy、 blood pressure、 left ventricular ejection fraction and estimated glomerular filtration rate were significantly different between the two groups（P0.05）;③multivariate analysis showed that eGFR,left ventricular hypertrophy and diabetic nephropathy（OR：1.26） were statistically significant.Conclusion Cardiovascular events are common complications of chronic kidney disease with many risk factors,we must pay close attention.

关 键 词：慢性肾脏疾病 心血管事件 

分 类 号：R692[医药卫生—泌尿科学]