电针遏制癫痫小发作的实验研究(一)  

Experimental Research in the Suppression of epileptic petit mal by electropuncture(Ⅰ)

作　　者：吴定宗[1] 万平[2] 张志雄[1] 曾庆元[1] 

机构地区：[1]上海中医药大学,200032 [2]华东师范大学,200062

出　　处：《上海针灸杂志》1999年第6期32-33,共2页Shanghai Journal of Acupuncture and Moxibustion

基　　金：上海市教委资助

摘　　要：目的　观察电针遏制癫痫小发作的效应及中枢机制。　方法　在癫痫小发作的大鼠模型上，电针督脉穴位“大椎”及“脊中”。　结果　电针可遏制小发作时产生的棘慢波。电针频率以高频８０ Ｈｚ较好。　结论　电针可明显降低大脑皮层兴奋性，并加强其抑制过程，从而遏制痫波。丘脑中一些核团对痫波分别有促进或遏制作用。Objective To investigate the inhibitory effect of electropuncture on epileptic petit mal and its underlying mechanism. Method Points on Du Channel, Dazhui (GV 14) and Jizhong (GV 6), were electropunctured in rat model of this epilepsy. Results Electropuncture could suppress spike and slow wave due to the epilepsy. A high electropuncture frequency of 80 Hz had a better effect. Conclusion Electropuncture can markedly reduce the excitability of cerebral cortex and strengthen the inhibitory process, checking epilepsy wave. Some intrathalamic nuclei have a promoting or inhibiting effect on epilepsy wave.

关 键 词：癫痫 发作 电针疗法 实验研究 

分 类 号：R277.721[医药卫生—中医学] R246.6