邻杂环(噁二唑)甲酰苯胺类化合物的设计合成及杀虫活性初步研究  

Design & Synthesis and Insecticidal Activity of Oxadiazole Benzamide Derivatives

作　　者：张湘宁[1] 马海军[1] 张雁南[1] 顾林玲[1] 刘丽[1] 张红芬[1] 俞晓妹[1] 李钰浩[2] 陈凯[2] 倪珏萍[1] 

机构地区：[1]江苏省农药研究所股份有限公司,南京210046 [2]南京工业大学理学院,南京210009

出　　处：《现代农药》2011年第3期17-19,23,共4页MODERN AGROCHEMICALS

基　　金：国家"十一五"科技支撑计划(No2006BAE01A01–3)

摘　　要：以超高效杀虫剂氯虫苯甲酰胺为先导,在酰胺部分引入了邻杂环(噁二唑),设计并合成了16个含邻杂环(噁二唑)甲酰苯胺类新化合物。生测结果表明,化合物普遍具有高杀虫活性,在10 mg/L剂量下对小菜蛾的致死率均大于80%。本研究结果为该类化合物的创制提供了参考。Excellent insecticide,chlorantranilipeole,was used by leading compound and sixteen novel 3-bromo-N-[4-X-2-methyl-6-oxadiazole]-1-（3-chloro-2-pyridinyl）-1H-pyrazole-5-carboxamide derivatives were designed and synthesi-zed.The preliminary bioassay showed that all compounds exhibited good insecticidal activity against Diamondback moth.The death rates were above 80 percent after 3day by feeding containing-pesticide leaf at 10mg/L.It was useful for research of oxadiazole benzamide derivatives.

关 键 词：邻杂环(噁二唑)甲酰苯胺类 合成 杀虫活性 

分 类 号：TQ453.2[化学工程—农药化工]