喜辽妥软膏防治化疗性静脉炎的效果观察  

The efficacy of hirudoid ointment for chemotherapy-induced phlebitis

作　　者：谢佐卿[1] 石金秀[2] 刘德忠[2] 姚春花[1] 

机构地区：[1]汕头市妇幼保健院护理部,515041 [2]汕头市妇幼保健院外妇科,515041

出　　处：《国际医药卫生导报》2011年第11期1391-1393,共3页International Medicine and Health Guidance News

摘　　要：目的探索一种操作简单、疗效显著、医护人员及病人乐于接受的预防和治疗化疗性静脉炎的方法。方法将使用环磷酰胺、5-氟脲嘧啶、表阿霉素化疗的住院病人随机分为实验组与对照组：实验组40例应用喜辽妥软膏在穿刺处周嘲并沿血管走向涂抹10～15cm，每天2次，每次化疗后继续涂抹3天；对照组41例则按传统静脉炎处理方法，用50％硫酸镁湿敷，每天2次，每次化疗后继续涂抹3天。结果两组病人静脉炎发生率分别为22．50％，67．29％（P〈0．05）。发生的静脉炎分级比较，疼痛缓解时间和炎症消除时间实验组均低于对照组，差异有显著性（P〈0．05）。结论喜辽妥软膏局部涂抹能有效减少环磷酰胺、5-氟脲嘧啶、表阿霉素所致的化学性静脉炎的发生，减轻静脉炎发生的程度，保证了化疗的正常进行，值得推广应用。Objective To explore a simple, effective therapy in the prevention and treatment of chemotherapy-induced phlebitis which medical staff and patients are all willing to use. Methods 81 patients who received chemotherapy with cydophosphamide, 5-fluorouracil, and pharmorubicin were randomly divided into two groups study group（ n = 40 ）and control group（ n = 41 ）. In the study group, hirudoid was applied around the puncture point and along the direction of the vessel of 10 - 15cm, twice daily for three days after the start of chemotherapy. The control group received traditional therapy for phlebitis - wet dressing with 50% magnesium sulfate, twice daily for three days. Results The incidence of phlebitis was 22.50% in hirudoid group and 67.29% in magnesium sulfate group （ P〈 0.05 ）. The time of pain-relief and that of inflammation elimination were shorter in the study group than in the control group （P 〈 0.05 ）. Conclusions Topical hirudoid can effectively reduce the incidence rate of cyclophosphamide-, 5-fluorouracil-, and pharmorubicin-induced phlebitis, reduce the degree of phlebitis, and ensure the process of chemotherapy. It is worth popularizing.

关 键 词：喜辽妥 静脉炎 效果观察 

分 类 号：R473.73[医药卫生—护理学]