药物洗脱支架治疗冠状动脉无保护左主干狭窄的疗效分析  

Clinical outcomes of drug stents in treating unprotected left main coronary stenosis

作　　者：郑若龙[1] 陈新军[1] 钱惠东[1] 李伟章[1] 蒋文龙[1] 魏峰[1] 徐卓文[1] 张华[1] 

机构地区：[1]东南大学医学院附属江阴医院心脏病科,江阴市214400

出　　处：《江苏医药》2011年第11期1293-1295,共3页Jiangsu Medical Journal

摘　　要：目的分析经皮冠状动脉介入术(PCI)药物洗脱支架治疗冠状动脉无保护左主干狭窄的疗效。方法无保护左冠状动脉主干病例45例,26例行药物支架治疗(PCI组),19例行冠状动脉搭桥治疗(CABG)组,比较两组住院期间、术后6个月及12个月心血管事件发生情况。结果 PCI组平均住院(7.1±2.3)d,短于CABG组的(13.1±4.2)d(P<0.01)。住院期间PCI组心血管事件7例,CABG组4例;术后6个月PCI组心血管事件12例,CABG组8例;术后12个月PCI组心血管事件17例,CABG组11例。三个时间段两组差异均无统计学意义(P>0.05)。结论与CABG比较,PCI治疗冠状动脉无保护左主干狭窄具有手术创伤小、术后恢复快和不增加术后心血管事件等优点。Objective To analyze the clinical outcomes of drug stents in treating unprotected left main coronary stenosis.Methods Of 45 patients with left main coronary artery stenosis,26 cases were treated with drug stents by percutaneuos coronary intervention（group PCI） and 19 cases underwent coronary artery bypass grafting（group CABG）.The events of cardiovascular diseases（CVD） were compared during hospital stay（T1）,after six month（T2） and twelve month（T3）.ResultsThe hospital stay was shorter in group PCI than that in group CABG[（7.1±2.3） days vs.（13.1±4.2） days]（P0.01）.The events of CVD at T1,T2 and T3 were seen in 7 cases,12 cases and 17 cases in group PCI,which were 4 cases,8 cases and 11 cases,respectively,in group CABG.There were no significant differences between two groups（P0.05）.Conlusion Compared to CABG,trenting the patients with left main coronary artery stenosis with drug stents has the advantages of less trauma,quicker recovery and without increase of CAD events.

关 键 词：左主干狭窄 经皮冠状动脉介入术 冠状动脉旁路移植术 

分 类 号：R541[医药卫生—心血管疾病]