原发性膀胱淀粉样变1例报告并文献复习  

Primary Amyloidosis of the Bladder:Report of 1 Cases and Review of Literature

作　　者：朱寅杰[1] 张连华[1] 薄隽杰[1] 沙建军[1] 吕坚伟[1] 黄旭元[1] 刘东明[1] 黄翼然[1] 

机构地区：[1]上海交通大学医学院附属仁济医院泌尿外科,上海200001

出　　处：《临床泌尿外科杂志》2011年第6期449-451,454,共4页Journal of Clinical Urology

基　　金：上海市科委自然科学基金(编号09ZR14180000)

摘　　要：目的:探讨原发性膀胱淀粉样变的临床、影像学、病理学特征以及诊疗方法。方法:回顾性分析1例原发性膀胱淀粉样变患者的临床资料。结果:行经尿道电切(TUR)术,术后辅以50%二甲基亚砜(DMS0)膀胱灌注,随访1年未出现肉眼血尿。结论:原发性膀胱淀粉样变临床及其罕见,极易与膀胱癌混淆,确诊需依据临床表现、影像学检查、病理学检查及特殊染色。治疗以手术尽可能切除病变组织为主,术后辅以DMS0膀胱灌注,疗效及预后良好。Objective：To detect the clinical, radiological, pathological featui＇es diagnostic and therapic methods of primary amyloidosis of the bladder. Methods：Reviewed 1 case of primary amyloidosis of the bladder in our hospi- tal. Results：The patient received TURBT with 50~DMSO instillation, no more gross hematuria was found in the 1 year follow-up. Conclusions：Primary amyloidosis of the bladder is uncommon. Primary localized bladder amyloidosis may be clinically as well as cystoscopicall y indistinguishable from transitional cell carcinoma. Definitive diagnosis rests on clinical, radiological features and histopatho[ogic examination of a biopsy specimen and special staining. The rules of the treatments include resecting the lesions as more as possible. DMSO bladder instillation is helpful. The outcome of the disease is good.

关 键 词：膀胱淀粉样变 原发性 手术治疗 

分 类 号：R694[医药卫生—泌尿科学]