噪声对小鼠细胞免疫功能的影响  

Effects of Noise on Cellular Immune Function in Mouse

作　　者：雷立建[1] 刘书乾[1] 

机构地区：[1]山西医科大学劳动卫生教研室,太原030001

出　　处：《中国公共卫生》1999年第12期1074-1075,共2页Chinese Journal of Public Health

摘　　要：为研究噪声对免疫系统的影响，模拟噪声作业环境强度特点，采用免疫毒理学方法，对暴露在１０５ｄＢ（ Ａ） 、９０ｄＢ（ Ａ） 、７５ｄＢ（Ａ） 噪声环境中的小鼠部分细胞免疫功能进行测定。结果表明：接噪组小鼠淋巴细胞增殖功能显著低于对照组，且有随噪声强度增加，细胞增殖功能降低的趋势。而细胞因子白细胞介素２ 的活性未见有明显变化。Effects of noise on cellar immune function in mouse which exposed to noise(the intensity was simulated noise work,105dB(A),90dB(A),75dB(A) respectively) was determined by the method of immunotoxicology.The results have been demonstrated that the stress induced showed a significant decrease in proliferative ability of lymphocyte.But the activity of IL 2 had no significant change.Preliminary estimates that noise had potential immune supression.

关 键 词：噪声 细胞免疫 T细胞 白细胞介素2 

分 类 号：R392.12[医药卫生—免疫学] TB53[医药卫生—基础医学]