沙漠干热环境15kg负重应激行军对人体HSP27的影响  

Effects of Marching with 15kg in Dry heat Desert on the Heat Shock Protein 27 of Humen

作　　者：刘兵[1] 陈胜[2] 徐文[1] 邬堂春[2] 张雪玲[1] 吴志豪[1] 

机构地区：[1]兰州军区联勤部军事医学研究所,兰州730020 [2]同济医科大学职业医学研究所

出　　处：《中国公共卫生》1999年第12期1084-1085,共2页Chinese Journal of Public Health

摘　　要：为探讨沙漠干热环境负重应激行军（ 热休克蛋白２７）（ ＨＳＰ２７） 的变化规律，对在沙漠干热环境中１５ｋｇ 负重，以不同速度和时间行军的５６ 名战士和１４ 名对照血浆ＨＳＰ２７ 进行了研究。结果发现，１５ｋｇ 负重情况下，以３－５ｋ ｍ ／ｈ 和５ｋ ｍ／ｈ 速度行军，各不同行军时间组ＨＳＰ２７ 明显增高（Ｐ＜ ０－０１） 。虽然３－５ｋ ｍ ／ｈ 行军２ 、３ 小时组ＨＳＰ２７ 明显高于行军１ 小时（Ｐ ＜０－０５） ，但５ｋ ｍ ／ｈ 各不同行军时间组同一行军时间的不同行军速度之间无差异（Ｐ＞ ０－０５） 。该结果提示，沙漠干热负重应激行军ＨＳＰ２７ 的表达在最初２ 小时最为活跃，行军２ 小时达高峰；ＨＳＰ２７ 的降解大约在行军１ 小时后加速， 行军２ 小时ＨＳＰ２７To explore the ergulation of heat shock protein 27(HSP27) in case of marching with 15kg in dry heat desert,the plasmas HSP27 of 56 marchers and 14 controls were detected.The results revealed that there is significant difference between exposed groups and control(P<0 01),and between for 1 hour and 2 or 3 hours at 3.5km/h(P<0 05),but there is no significant difference between different time exposures at 5km/h,at 3.5km/h and 5km/h for the same time.It was in the first 2 hours that HSP27 was expressed the most actively,and in he second hour that HSP27 degraded the most quickly.After marching for 2 hours,a new balance between the synthesis and consumption of HSP27 regained

关 键 词：干热 沙漠 HSP27 应激行军 负重 热休克蛋白 

分 类 号：R339.53[医药卫生—人体生理学]