间接血凝法(IHA)检测肺炎支原体抗体在儿童呼吸道感染诊治中的临床应用  

Clinical application of mycoplasma pneumonia antibody detection with indirect haemagglutination assay in children respiratory passage infection

作　　者：冯永钦[1] 张清平[1] 潘红玲[1] 孙勇[1] 

机构地区：[1]枝江市人民医院,湖北枝江443200

出　　处：《中国实验诊断学》2011年第5期849-850,共2页Chinese Journal of Laboratory Diagnosis

摘　　要：目的探讨用间接血凝法检测肺炎支原体抗体(Mp-Ab)在儿童呼吸道感染诊断中的临床应用价值。方法用间接血凝法检测经临床确诊的50例肺炎支原体肺炎患儿和30例非呼吸道感染儿童、535例儿童呼吸道感染患儿的肺炎支原体抗体(Mp-Ab)的感染状况和结果并进行比较。结果通过对50例肺炎支原体肺炎患儿和30例非呼吸道感染患儿的肺炎支原体抗体的检测,敏感性达到92.6%,特异性达到93.3%。在535例儿童呼吸道感染的检测中,阳性率为22.8%。<3周岁阳性率为12.1%,3-6岁阳性率为29.3%,6-12岁阳性率为17.9%。结论间接血凝法(IHA)检测肺炎支原体抗体操作方法简便,价格低廉,实验不要求特殊条件,易于在基层医院推广应用,对早期儿童呼吸道肺炎支原体感染的诊断有重要的临床意义。Objective to explore clinical application value of mycoplasma pneumonia antibody detetion with indirect haemagglutination assay in children respiratory passage infection.Methods 50 cases with mycoplasma pneumonia infection by clinical definite and 30 cases with non-respiratory infection;to contrast the infection state of mycoplasma pneumonia in 535 cases respiratory infection in children.Results the sensitivity was 92.6% and specificity was 93.3% in indirect haemagglutination assay in 50 cases with mycoplasma pneumonia infection by clinical definite;the masculine rate was 22.8% in 535 cases respiratory infection;the masculine rate in group of under 3 years was 11.4%,between 3 and 6 years was 29.3%,6 and 12 years was 17.9%.Conclusion mycoplasma pneumonia antibody detection with indirect haemagglutination assay could be applied clinically because of the simplicity of the operation and cheap price.

关 键 词：间接血凝法(IHA) 肺炎支原体 儿童呼吸道感染 

分 类 号：R725.6[医药卫生—儿科]