不同生活习性下原核生物基因组大小与GC含量的关系研究  

Correlation Between Genome Size and GC Content in Prokaryotes with Different Lifestyles

作　　者：林瀚[1] 黄亚志[1] 张尚宏[1] 

机构地区：[1]中山大学基因工程教育部重点实验室∥生物工程研究中心,广东广州510275

出　　处：《中山大学学报（自然科学版）》2011年第3期90-93,共4页Acta Scientiarum Naturalium Universitatis Sunyatseni

基　　金：国家自然科学基金资助项目(30270752);广东省自然科学基金资助项目(031616);国家973计划资助项目(2005CB724600);国家人才基金(基地)项目(J0730638)

摘　　要：对原核生物基因组的研究显示,基因组GC含量与基因组大小和氧气偏好性等因素存在着一定的相关性。为了探索基因组大小与GC含量的相关性是否受原核生物生活习性的影响,选取了有代表性的411种原核生物(包括古细菌与真细菌),分别从最适生长温度、氧气偏好性、运动特性、水生特性和寄生特性等因素进行分析,发现基因组大小与GC含量的相关性确实受这些因素的影响,而寄生原核生物中显示出最好的相关性。Researches of prokaryotic genomes have led to the discovery of the correlation of genomic GC content with genome size and aerobics/anaerobics.In order to study the influence of lifestyle of prokaryotes on the correlation between genome size and genomic GC content,we analyzed the effect of optimal growth temperature,aerobics/anaerobics,motility,aquatics,and parasitism,using data from 411 representative prokaryotic species（including archaea and bacteria） and correlation/regression approaches.The results show that the correlation between genome size and genomic GC content is indeed influenced by these factors.Moreover,it was found that the correlation is the most significant in parasitic prokaryotes.

关 键 词：原核生物 基因组大小 GC含量 生活习性 相关/回归分析 

分 类 号：Q754[生物学—分子生物学]