人参皂苷Rd的药理作用研究进展  

Advances in the research of pharmacological effects of ginsenoside Rd

作　　者：张琛[1] 赵钢[1] 

机构地区：[1]第四军医大学西京医院神经内科,西安710032

出　　处：《中国新药杂志》2011年第11期953-958,共6页Chinese Journal of New Drugs

基　　金：国家"重大新药创制"科技重大专项(2008ZX09101-026)

摘　　要：人参皂苷Rd(ginsenoside Rd,GSRd)是人参皂苷的主要活性单体之一,属于达玛烷型人参皂苷中的二醇型。GSRd在人参属植物中的含量较低,但却具有较强的生物活性,其药理作用受到国内外学者的广泛关注。研究表明,GSRd能够保护心血管及肾脏功能,发挥抗肿瘤、调节免疫等多种药理作用,对于中枢神经系统亦显示出良好的神经保护效应。文中对人参皂苷Rd的药理作用特别是人参皂苷Rd的神经保护作用进行了综述。Ginsenoside Rd （GSRd） is one of the major active components of ginsenosides, which belongs to the panaxadiol group of dammarane tent bioactivity has been paid more att glycos ention ides. Although the content of GSRd in Panax is relatively low, its poby scientists. Recently, GSRd has been verified to produce various pharmacological actions, such as protection of cardiovascular and renal function, anti-cancer effects and re of immune responses. Moreover, GSRd exhibits neuroprotective effects on the central nervous system. In this review, we summarized the pharmacological effects of ginsenoside Rd especially the neuroprotective effects central nervous system in detail.

关 键 词：人参皂苷RD 生物活性 神经保护 

分 类 号：R284.1[医药卫生—中药学]