肝胆管结石患者胆总管切开取石术后Oddi括约肌肌电的研究  

Characteristics of electromyography of sphincter of Oddi in patients with cholelithiasis after common bile duct exploration

作　　者：许兆龙[1] 陈飞[1] 刘永康[1] 李智华[1] 

机构地区：[1]第三军医大学西南医院全军肝胆外科研究所、中国人民解放军西南肝胆外科医院,重庆400038

出　　处：《中华消化外科杂志》2011年第3期203-205,共3页Chinese Journal of Digestive Surgery

基　　金：重庆市科技攻关项目（2009AC5020）x

摘　　要：目的研究肝胆管结石患者胆总管切开取石术后Oddi括约肌（SO）肌电的特点，旨在寻找临床研究、检测SO功能的新方法。方法对2010年1月至10月在第三军医大学西南医院复诊的33例行胆总管切开取石术的肝胆管结石患者经T管窦道胆道镜辅助行SO压力与肌电检测，根据SO测压结果将33例患者分为低压力组、正常压力组及高压力组，比较各组患者s0峰电位丛（SOSB）幅值、频率和持续时间。结果低压力组、正常压力组、高压力组患者分别有14、13、6例，平均SO基础压力分别为（3．1±1．2）、（18．5±7．6）、（39．8±4．8）mmHg（1mmHg=0．133kPa）。低压力组、正常压力组、高压力组患者SOSB幅值、频率、持续时间分别为（41±27）、（150±71）、（301±109）μV，（5．8±1．6）、（6．9±1．4）、（7．8±1．2）次／min，（2．7±0．6）、（3．4±0．7）、（4．2±0．7）S，各组比较，差异有统计学意义（F=50．751，4．293，13．159，P〈0．05）。结论SO肌电检测可以从电生理的层面反映SO的功能，有望成为临床研究、检测SO功能的新方法。Objective To observe the characteristics of electromyography of sphincter of Oddi （SO） in patients with cholelithiasis after common bile duct exploration, and investigate new methods for detecting the motility of SO. Methods The basal pressure of SO （SOBP） and electromyography of SO were detected in 33 patients with cholelithiasis who were reexamined at the Southwest Hospital from January to October, 2010. All patients were divided into low SOBP group, normal SOBP group and high SOBP group. The amplitude, frequency and duration of SO spike burst （SOSB） of the three groups were compared. Results The numbers of patients in the low SOBP group, normal SOBP group and high SOBP group were 14, 13 and 6, respectively. The mean SOBP of the low SOBP group, normal SOBP group and high SOBP group were （3.1±1.2）, （ 18.5±7.6）, （39.8±4.8） mm Hg （1 mm Hg=0. 133 kPa）. The amplitude, frequency and duration of SOSB were （41±27）pN, （5.8±1.6） times/minutes and （2.7± 0.6） s in the low SOBP group, and （ 150± 71 ） μV, （6.9±1.4） times/minutes and （3.4±0.7） s in the normal SOBP group, and （ 301±109） μV, （7.8± 1.2 ） times/minutes and （4.2±0.7 ） s in the high SOBP group, respectively, with significant difference among the three groups （F = 50. 751, 4. 293, 13. 159, P 〈0. 05 ）. Conclusion The results of electromyography of SO could reflect the function of SO, and it is possible to be a prospective method in the clinical research of SO.

关 键 词：胆石症 ODDI括约肌 电生理 

分 类 号：R657.4[医药卫生—外科学]