呼吸机高压氧舱内吸氧对重型颅脑损伤后应激性溃疡出血的影响  

Effect of Oxygen Inhalation in Hyperbaric Oxygen Chamber on Stress Ulcer Bleeding after Severe Craniocerebral Injury

作　　者：温剑峰[1,2] 莫晔[2] 钱锁开 杨琦帆[2] 滕劲忠[2] 夏瑜[2] 

机构地区：[1]南昌大学研究生院医学部,2010级南昌330006 [2]中国人民解放军第94医院神经外科,南昌330002

出　　处：《南昌大学学报（医学版）》2011年第2期16-17,27,共3页Journal of Nanchang University：Medical Sciences

基　　金："十一五"军队医药卫生科研项目(06MA76)

摘　　要：目的探讨呼吸机高压氧舱内吸氧对重型颅脑损伤后应激性溃疡出血的影响。方法将108例重型颅脑损伤患者按随机数字表法分为2组:治疗组和对照组,每组54例。对照组给予常规治疗,采用奥美拉唑静脉滴注预防应激性溃疡出血;治疗组在对照组治疗的基础上采用呼吸机高压氧舱内吸氧治疗。观察2组患者应激性溃疡出血的发生情况。结果治疗组、对照组患者应激性溃疡出血的发生率分别为14.8%、40.7%,2组比较差异有统计学意义(χ2=5.481,P<0.05)。结论应用呼吸机高压氧舱内吸氧治疗重型颅脑损伤患者可降低应激性溃疡出血的发生率。Objective To explore the effect of hyperbaric oxygen chamber oxygen inhalation therapy on the ventilator in hemorrhagic of stress ulcer after with severe type craniocerebral injury patients.Methods One hundred and eight cases of severe type craniocerebral injury patients were randomly divided into 2 groups to number table method：the treatment group and the control group,with 54 cases in each group.The control group patients received conventional therapy,prevention of intravenous drip of Omeprazole in stress ulcer.Treatment group were control group treated based on the use of ventilator in hyperbaric oxygen chamber oxygen inhalation therapy.Observed 2 groups in patients of occurred situation in stress ulcer hemorrhagic.Results The treatment group and control group in patients with stress ulcer hemorrhagic occurred rates 14.8%,40.7%,The difference between 2 groups was statistically significant（χ2=5.481,P0.05）.Conclusion The applications hyperbaric oxygen chamber oxygen inhalation therapy of stress ulcer hemorrhagic may be lower occurred rates in severe type craniocerebral injury patients.

关 键 词：重型颅脑损伤 应激性溃疡 出血 呼吸机 高压氧舱 高压氧 奥美拉唑 

分 类 号：R651.1[医药卫生—外科学]