不同参数电针刺激对糖耐量受损患者血糖的影响  

Effects of Different Frequencies of Electroacupuncture on Blood Glucose Level in Impaired Glucose Tolerance Patients

作　　者：孟宏[1] 郝晋东[2] 王宏才[1] 赵嘉勇[3] 赵臣来[4] 翟煦[1] 

机构地区：[1]中国中医科学院针灸研究所,北京100700 [2]武警总医院中西医康复科,北京100039 [3]中国医科大学北京顺义区医院中医科,北京101300 [4]北京大学首钢医院针灸科,北京100041

出　　处：《针刺研究》2011年第3期220-223,共4页Acupuncture Research

基　　金：中国中医科学院团队创新项目(No.ZZ2006082)

摘　　要：目的:观察不同频率电针干预糖耐量受损患者的临床效果。方法:对120例糖耐量受损患者经糖尿病宣教后,随机分为空白对照组和3组不同频率电针干预治疗组。电针组取双侧脾俞、肾俞、足三里、三阴交穴,频率分别为5、501、00 Hz,电流强度1 mA,连续波,持续20 min。每日治疗1次,10次为1个疗程,共治6个疗程。监测各组治疗前后人体质量指数、空腹血糖、餐后2 h血糖、糖化血红蛋白变化。结果:对照组治疗前后人体质量指数、空腹血糖、餐后2 h血糖、糖化血红蛋白无明显变化(P>0.05);电针干预50 Hz、100 Hz组在疗程结束后,人体质量指数、空腹血糖、餐后2 h血糖、糖化血红蛋白亦无明显变化(P>0.05);电针干预5 Hz组治疗后餐后2 h血糖、糖化血红蛋白明显下降,与本组治疗前及与对照组比较差异均有统计学意义(P<0.01,P<0.05)。结论:糖耐量受损患者在饮食调控、适当运动基础上结合低频电针干预有利于餐后2 h血糖、糖化血红蛋白等指标的恢复。Objective To investigate the clinical efficacy of electroacupuncture （EA） at different frequencies for patients with impaired glucose tolerance （IGT）. Methods A total of 120 IGT outpatients were randomly divided into control, EA-5 Hz, EA-50 Hz, and EA-100 Hz groups （n = 30/group）. EA （1 mA） was applied to bilateral Pishu （BL 20）, Shenshu （BL 23）, Zusanli （ST 36） and Sanyinjiao （SP 6） for 20 min, once daily for 60 sessions. Body mass index （BMI）, fasting blood glucose （FBG） and 2-hour post-prandial blood glucose （2 h PBG） contents were detected by using BAYER Blood Sugar Analyzer and glycosylated haemoglobin （HbAlc） content was detected by enzymatic assay. Results Following the treatment, both HbAlc and 2 h PBG levels in the EA-5 Hz group were significantly lower than those of the control group and those of pre-treatment in the same one group （P〈0.05, P〈0.01）. No significant differences were found between the EA-5 Hz and control groups, between pre-treatment and post-treatment in the EA-5 Hz group in BMI and FBG levels; between the EA-50 Hz and control groups, between the EA-100 Hz and control groups, and between pre-treatment and post-treatment in the EA-50 Hz and EA-100 Hz groups in BMI, FBG,2 h PBG and HbAlc levels （P〈0.05）. Conclusion Lower frequency EA of BL 20, BL 23, ST 36 and SP 9 can reduce HbAlc and 2 h PBG levels in IGT patients, suggesting a helpful effect of EA in controlling the development of diabetes.

关 键 词：糖耐量受损 电针 低频电针 血糖 糖化血红蛋白 

分 类 号：R246.1[医药卫生—针灸推拿学]