育龄期慢性乙型肝炎女性患者的抗病毒治疗  

Antiviral therapy of chronic hepatitis B in women of childbearing age

作　　者：祁丹[1] 易建华[1] 沈贵月[1] 

机构地区：[1]华中科技大学同济医学院附属协和医院感染病科,湖北省武汉市430022

出　　处：《世界华人消化杂志》2011年第15期1634-1638,共5页World Chinese Journal of Digestology

摘　　要：本文介绍了近年来育龄期慢性乙型肝炎女性患者抗病毒治疗的一些研究结果,分析了育龄期女性干扰素的应用、核苷(酸)类药物在妊娠患者中应用的临床依据以及核苷(酸)类药物在阻断乙型肝炎病毒母婴传播中的意义及母乳喂养问题,指出对于育龄期未怀孕患者来说首选干扰素治疗,同时对于妊娠的患者来说,选择相对安全的核苷(酸)类药物抗病毒治疗可以起到降低宫内感染,降低肝脏病变等作用.This paper introduces the recent research results about antiviral therapy of chronic hepatitis B in women of childbearing age.It addresses several key issues,including the application of interferon in women of childbearing age;clinical evidence and treatment problems for the application of nucleoside analogues in pregnant patients;and significance of nucleoside analogues in blocking mother-to-child transmission and breastfeeding problems.Interferon-based therapy is preferable for women of childbearing age.Pregnant women may choose relatively safe nucleoside analogues to reduce perinatal transmission and liver injury.

关 键 词：慢性乙型肝炎 育龄期 抗病毒治疗 

分 类 号：R512.62[医药卫生—内科学]