1266例患者支原体检测阳性率与耐药性分析  

Clinical analysis of mycoplasma infection rate and its drug resistance in 1 266 cases

作　　者：欧成举[1] 李小宁[1] 俞璇[1] 

机构地区：[1]皖南医学院弋矶山医院,安徽芜湖241000

出　　处：《检验医学与临床》2011年第10期1168-1169,1172,共3页Laboratory Medicine and Clinic

摘　　要：目的了解本地区泌尿生殖道炎性反应患者支原体检测阳性率及耐药性分析,为临床合理应用抗生素提供依据。方法应用尿素-精氨酸培肉汤培养基法,对1 266例泌尿生殖道标本进行支原体培养及13种药物的药敏试验,并对结果进行统计学分析。结果 1 266例患者中支原体阳性408例(32.2%),其中解脲支原体(Uu)感染321例;人型支原体(Mh)感染62例;Uu与Mh混合感染25例。药敏试验结果显示,对强力霉素、美满霉素敏感率分别为96%、93%。对林可霉素、诺氟沙星、环丙沙星的耐药率分别为88%、80%、80%。结论临床标本中生殖道支原体的感染率及耐药率较高。进行耐药性检测十分必要,可为临床治疗提供依据。Objective To understand the mycopasma infection rate and its drug resistance in patients with uro- genital tract inflammatory in our area, and the rational use of antibiotics. Methods A total of 1 266 cases were testesd by the urea and arginine brothculture method,the result of positive rate and drug resistance were analyzed respectively. Results 408 out of 1 266 patients were tested mycopasma positive（32.2%）, 321 samples were Uu infee tion ; infection of Mh were 62 cases;mixed infection of Uu and Mh were 25 cases. The result showed the high sensitive rates of doxycycline and minocycline were 96% and 93%, and drug resistance rate of lincomyein, no rfloxacin, ciprofloxacinis were 88%,80%,80% respectively. Conclusion There is a high positive rate of mycopasma infection in the clinics, so it is essential to monitor drug resistance and the treatment of mycopasma infection should be chosen according to the result of drug sensitivity test.

关 键 词：泌尿生殖道感染 支原体 抗生素 耐药性 

分 类 号：R691.3[医药卫生—泌尿科学]