胎儿骨骼发育影响因素的研究进展  

Progress in research on influencing factors of fetal bone development

作　　者：吴莉萍[1] 侯晓静[1] 

机构地区：[1]上海交通大学护理学院,上海200025

出　　处：《中国妇幼健康研究》2011年第3期383-386,共4页Chinese Journal of Woman and Child Health Research

基　　金：上海交通大学医学院自然科学基金资助项目（09XJ21055）

摘　　要：强健的骨骼对人的一生是至关重要的,胎儿期和出生后的早期骨营养状况将会影响人体一生的骨骼发育过程.该文主要阐述了胎儿期骨骼发育演变情况,并结合近年来相关文献,发现遗传因素、维生素D、钙、磷、铅、甲状旁腺激素水平、转化生长因子-β、骨形成发生蛋白、疾病、药物等因素都对胎儿骨骼的发育会产生影响,其中钙对胎儿骨骼发育起着尤为重要的作用.因此为促进胎儿骨骼发育,妊娠期间要重视孕妇营养状况并加以正确的指导.Strong bones are essential to human life. The prenatal and early postnatal bone nutritional status will affect the bone development of human＇ s whole life. With the literature in recent years this paper described the evolution of bone development during fetal period and influencing factors of fetal bone development including genetic factors, vitamin D, calcium, phosphorus, lead, parathyroid hormone level, transforming growth factor-beta, bone morphogenetic protein, disease, drug and so on. Among these factors, calcium plays an important role in influencing the bone development of fetus. To promote the bone development of fetus, attention and proper guidance should be paid to the nutritional status of pregnant women during pregnancy.

关 键 词：胎儿 骨骼发育 钙 影响因素 

分 类 号：R714.5[医药卫生—妇产科学]