健脾温肾、清热活血方联合整肠生治疗慢性复发型溃疡性结肠炎  

Traditional Chinese Medicine Decoction and Probiotics in the Treatment of Chronic Intermittent Ulcerative Colitis

作　　者：张援[1,2] 林一帆[1] 王长洪[1] 陆宇平[1] 巩阳[1] 刘杨[1] 季芳[1] 

机构地区：[1]中国人民解放军沈阳军区总医院中医科国家消化病重点专科,辽宁沈阳110840 [2]辽宁中医药大学,辽宁沈阳110032

出　　处：《辽宁中医药大学学报》2011年第7期211-212,共2页Journal of Liaoning University of Traditional Chinese Medicine

摘　　要：目的:探讨健脾温肾、清热活血方联合整肠生治疗慢性复发型溃疡性结肠炎患者的疗效。方法:将60例慢性复发型溃疡性结肠炎患者随机分为试验组和对照组,各30例。试验组给予健脾温肾、清热活血方联合整肠生;对照组只给予上述中药方;疗程均为8周。观察两组患者治疗后临床症状改善状况、肠镜检查结果、复发情况及不良反应。结果:试验组治疗后临床综合疗效、肠镜检查结果及不良反应发生率与对照组的比较,差别均无统计学意义(P>0.05)。但在治疗2周时,在临床主要症状记分上,试验组低于对照组(P<0.05)。随访6个月,试验组3例复发,对照组12例复发。结论:健脾温肾、清热活血方联合整肠生治疗慢性复发型溃疡性结肠炎患者能够更快地控制临床症状,且明显减少复发。Objective ： To study the clinical efficacy and safety of Bacillus Licheniforrnis Capsules combined with Traditional Chinese Medicine decoction in patients with ulcerative colitis （ UC ）. Methods ： Sixty patients with chronic intermittent UC were randomly divided into two groups： trial group （n=30）and control group （ n=30 ）. The patients in the trial group were given Bacillus Licheniformis Capsules （ 500rag, 3 times daily ） combined with Traditional Chinese Medicine decoction, and those in the control group were given Traditional Chinese Medicine decoction only for 8 weeks. Clinical effects and safety were compared between two groups. Results ： After treatment, there no significant differences in the overall clinical efficacy, relief of clinical symptoms, remission in colonoscopy between the two groups （/9〉0.05 ）. The score of main symptom of trial group＇s lower than control group＇s （ P〈0.05 ）. The follow - up from sixmonths to one year showed there were 3 cases of relapse in the trial group while 12 cases of relapse in the control group. Conclusion ： Bacillus Licheniformis Capsules combined with Traditional Chinese Medicine decoction is faster than Traditional Chinese Medicine decoction only on control symptom of UC and could diminish the recurrence rate as well.

关 键 词：溃疡性结肠炎 中药 整肠生 

分 类 号：H313[语言文字—英语]