胰岛素泵治疗对初诊2型糖尿病的疗效观察  

Clinical observation of continuous subcutaneous insulin infusion therapy on newly type 2 diabetes mellitus

作　　者：薄亚文[1] 叶新华[1] 张煜[1] 

机构地区：[1]南京医科大学附属常州市第二人民医院内分泌代谢科,江苏213003

出　　处：《常州实用医学》2011年第3期159-161,共3页CHANGZHOU PRACTICAL MEDICINE

摘　　要：目的探讨胰岛素泵治疗初诊2型糖尿病的临床疗效。方法将90例初诊2型糖尿病患者随机分为两组，胰岛素泵持续皮下胰岛素输注（岱Ⅱ）组45例，多次胰岛素皮下注射（MSⅡ）组45例。两组均经为期两周的强化治疗，比较两组治疗前后空腹（FPG）、餐后2h血糖（2hPG）、糖化血红蛋白（HbAlc）和两组治疗所需胰岛素总用量、血糖达标时间、低血糖及黎明现象发生率。结果（1）两组均能显著降低患者血糖及HbAlc（P〈0．05）。（2）CSⅡ组胰岛素总用量、血糖达标时问少于／短于MSⅡ组（P〈0．05）。（3）CSⅡ组低血糖及黎明现象发生率低于MSⅡ组（P〈0．05）。结论胰岛素泵持续皮下胰岛素输注（CSⅡ）更符合生理性胰岛素分泌，安全性好，能更快控制血糖，节省胰岛素用量。Objective To investigate the Clinical efficacy of continuous subcutaneous insulin infusion（CSⅡ）in newly type 2 diabetes. Mothods The 90 patients with newly type 2 diabetes were randomly divided into CSII group（45 cases） and multiple subcutaneous insulin injection（MSⅡ）group（45 cases） .All were treated by 2 weeks intensive insulin treatment.＇Fne level of fasting plasma glucose（FPG）, 2 hours postprandial glucose（2hPG）, glycusylated hemoglobinAlc（ HbAlc） were compared before and after treatment The dosage of insulin, the contol time of blood glucose, the hypoglycemia and the dawn phenomenon were observed. Results Blood glucose could be controlled in patients.The dosage of insulin and the contol time of blood glucose were lower in CSⅡ group than MSH group. And the rates of the hypoglycemia and the dawn phenomenon were lower in CSⅡ group than MSⅡ group. Conclusion CSⅡ is better than MSⅡ in modifying physiological insulin secretion for newly type 2 diabetes mellitus patients.

关 键 词：胰岛素泵 初诊2型糖尿病 多次胰岛素皮下注射 

分 类 号：R58[医药卫生—内分泌]